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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC1A1 All Species: 27.27
Human Site: T499 Identified Species: 60
UniProt: P43005 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43005 NP_004161.4 524 57100 T499 L D N E D S D T K K S Y V N G
Chimpanzee Pan troglodytes XP_520467 524 57084 T499 L D N E D S D T K K S Y V N G
Rhesus Macaque Macaca mulatta XP_001085339 524 57205 T499 L D N E D S D T K K S Y V N G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P51906 523 56657 T498 L D N E D S D T K K S Y V N G
Rat Rattus norvegicus P51907 523 56753 T498 L D N E D S D T K K S Y V N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505613 485 52757 S460 L D N E E A E S K K S Y I N G
Chicken Gallus gallus XP_424930 527 57322 T502 L D N D E T E T K K S Y I N G
Frog Xenopus laevis NP_001083306 542 59629 E518 N S V I E E N E M K K P Y Q L
Zebra Danio Brachydanio rerio NP_001002666 526 57719 K502 D D D E C E D K K S Y V N G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10901 503 54657 I479 A T T R S H S I A M N D E K R
Sea Urchin Strong. purpuratus XP_781833 592 63937 D568 F N G K K M A D R K D S D L H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98.4 N.A. N.A. 90 91 N.A. 78 83.6 49.8 73.9 N.A. N.A. N.A. 48.6 48.1
Protein Similarity: 100 99.6 99 N.A. N.A. 94.8 95 N.A. 85.3 91.8 69 88.4 N.A. N.A. N.A. 65.4 63.1
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. 66.6 66.6 6.6 33.3 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 100 100 20 40 N.A. N.A. N.A. 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 10 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 73 10 10 46 0 55 10 0 0 10 10 10 0 0 % D
% Glu: 0 0 0 64 28 19 19 10 0 0 0 0 10 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 73 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 10 0 0 0 10 0 0 0 0 19 0 0 % I
% Lys: 0 0 0 10 10 0 0 10 73 82 10 0 0 10 0 % K
% Leu: 64 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % L
% Met: 0 0 0 0 0 10 0 0 10 10 0 0 0 0 0 % M
% Asn: 10 10 64 0 0 0 10 0 0 0 10 0 10 64 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 10 % R
% Ser: 0 10 0 0 10 46 10 10 0 10 64 10 0 0 0 % S
% Thr: 0 10 10 0 0 10 0 55 0 0 0 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 10 46 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 64 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _