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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF5
All Species:
15.15
Human Site:
T249
Identified Species:
30.3
UniProt:
P43026
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43026
NP_000548.1
501
55411
T249
L
R
K
K
P
S
D
T
A
K
P
A
A
P
G
Chimpanzee
Pan troglodytes
XP_001164592
501
55399
T249
L
R
K
K
P
S
D
T
A
K
P
A
A
P
G
Rhesus Macaque
Macaca mulatta
XP_001099702
499
55239
T247
L
R
K
K
P
S
D
T
A
K
S
A
A
P
V
Dog
Lupus familis
XP_542974
499
55131
T247
L
R
K
K
P
S
D
T
A
K
P
V
A
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P43027
495
54867
V243
L
R
K
K
P
L
D
V
A
K
P
A
V
P
S
Rat
Rattus norvegicus
Q6HA10
452
50994
Q229
L
R
P
Q
P
W
K
Q
L
C
L
E
L
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511410
181
19862
Chicken
Gallus gallus
Q90752
405
46039
S193
M
K
P
L
S
E
R
S
Q
A
I
T
R
L
L
Frog
Xenopus laevis
P25703
398
45557
A185
I
V
K
P
A
A
A
A
S
R
G
P
V
V
R
Zebra Danio
Brachydanio rerio
P85857
404
46271
L192
R
K
A
E
W
E
V
L
D
V
W
G
I
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
T282
L
L
T
K
S
A
N
T
V
R
S
F
T
H
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48969
461
51863
G229
L
R
E
R
G
S
D
G
S
R
S
P
V
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.8
96.4
N.A.
91.2
46.7
N.A.
28.1
28.9
26.9
42.5
N.A.
25.3
N.A.
N.A.
24.1
Protein Similarity:
100
99.4
98.1
97
N.A.
92.6
62
N.A.
32.7
43.1
42.5
56.2
N.A.
40.8
N.A.
N.A.
40.7
P-Site Identity:
100
100
86.6
86.6
N.A.
73.3
20
N.A.
0
0
6.6
0
N.A.
20
N.A.
N.A.
26.6
P-Site Similarity:
100
100
86.6
86.6
N.A.
73.3
26.6
N.A.
0
20
33.3
13.3
N.A.
40
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
17
9
9
42
9
0
34
34
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
50
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
9
9
0
17
0
0
0
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% F
% Gly:
0
0
0
0
9
0
0
9
0
0
9
9
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% I
% Lys:
0
17
50
50
0
0
9
0
0
42
0
0
0
0
17
% K
% Leu:
67
9
0
9
0
9
0
9
9
0
9
0
9
9
17
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
17
9
50
0
0
0
0
0
34
17
0
42
0
% P
% Gln:
0
0
0
9
0
0
0
9
9
0
0
0
0
0
0
% Q
% Arg:
9
59
0
9
0
0
9
0
0
25
0
0
9
9
9
% R
% Ser:
0
0
0
0
17
42
0
9
17
0
25
0
0
0
17
% S
% Thr:
0
0
9
0
0
0
0
42
0
0
0
9
9
0
0
% T
% Val:
0
9
0
0
0
0
9
9
9
9
0
9
25
9
9
% V
% Trp:
0
0
0
0
9
9
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _