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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GUCA1A All Species: 14.24
Human Site: S141 Identified Species: 26.11
UniProt: P43080 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43080 NP_000400.2 201 22920 S141 E F T D T V F S K I D V N G D
Chimpanzee Pan troglodytes XP_001174348 193 21804 G141 K I D V N G D G E L S L E E F
Rhesus Macaque Macaca mulatta XP_001086886 202 22999 S141 E F T D T V F S K I D V N G D
Dog Lupus familis XP_851487 205 23100 S141 E F T N T V F S K I D V N G D
Cat Felis silvestris
Mouse Mus musculus P43081 202 22979 A141 E F T D T V F A K I D I N G D
Rat Rattus norvegicus P62749 193 22320 D150 S T P E K R T D K I F R Q M D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508327 198 22788 T141 E F T D M V F T K I D I N G D
Chicken Gallus gallus P79880 199 22789 K140 F T N M V F D K I D I N G D G
Frog Xenopus laevis Q6DCM9 193 22267 D150 S T P E K R T D K I F K Q M D
Zebra Danio Brachydanio rerio A9JTH1 193 22206 E150 S T P E K R T E K I F R Q M D
Tiger Blowfish Takifugu rubipres NP_001027790 189 21769 D140 D F T N S V F D R I D I N G D
Fruit Fly Dros. melanogaster P42325 190 21875 T144 K M P E D E S T P E K R T D K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P36609 190 21967 R149 A D D S P R K R A K M I F E K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93 99 93.6 N.A. 91 41.7 N.A. 85.5 80.5 41.2 41.7 61.1 42.2 N.A. 30.8 N.A.
Protein Similarity: 100 94.5 99 97 N.A. 95.5 60.2 N.A. 93.5 90.5 60.2 61.1 75.1 58.7 N.A. 52.7 N.A.
P-Site Identity: 100 0 100 93.3 N.A. 86.6 20 N.A. 80 0 20 20 60 0 N.A. 0 N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 26.6 N.A. 93.3 0 26.6 26.6 93.3 20 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 16 31 8 0 16 24 0 8 47 0 0 16 70 % D
% Glu: 39 0 0 31 0 8 0 8 8 8 0 0 8 16 0 % E
% Phe: 8 47 0 0 0 8 47 0 0 0 24 0 8 0 8 % F
% Gly: 0 0 0 0 0 8 0 8 0 0 0 0 8 47 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 8 70 8 31 0 0 0 % I
% Lys: 16 0 0 0 24 0 8 8 62 8 8 8 0 0 16 % K
% Leu: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % L
% Met: 0 8 0 8 8 0 0 0 0 0 8 0 0 24 0 % M
% Asn: 0 0 8 16 8 0 0 0 0 0 0 8 47 0 0 % N
% Pro: 0 0 31 0 8 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 24 0 0 % Q
% Arg: 0 0 0 0 0 31 0 8 8 0 0 24 0 0 0 % R
% Ser: 24 0 0 8 8 0 8 24 0 0 8 0 0 0 0 % S
% Thr: 0 31 47 0 31 0 24 16 0 0 0 0 8 0 0 % T
% Val: 0 0 0 8 8 47 0 0 0 0 0 24 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _