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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GUCA1A
All Species:
22.73
Human Site:
T169
Identified Species:
41.67
UniProt:
P43080
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43080
NP_000400.2
201
22920
T169
K
D
Q
M
L
L
D
T
L
T
R
S
L
D
L
Chimpanzee
Pan troglodytes
XP_001174348
193
21804
D167
D
T
L
T
R
S
L
D
L
T
R
I
V
R
R
Rhesus Macaque
Macaca mulatta
XP_001086886
202
22999
T169
K
D
Q
M
L
L
D
T
L
T
R
S
L
D
L
Dog
Lupus familis
XP_851487
205
23100
T169
K
D
Q
M
L
L
D
T
L
T
R
S
L
D
L
Cat
Felis silvestris
Mouse
Mus musculus
P43081
202
22979
T169
K
D
Q
M
L
L
D
T
L
T
R
S
L
D
L
Rat
Rattus norvegicus
P62749
193
22320
S178
K
G
A
K
S
D
P
S
I
V
R
L
L
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508327
198
22788
T169
K
D
E
M
L
L
D
T
L
T
R
S
L
D
L
Chicken
Gallus gallus
P79880
199
22789
I167
K
D
E
V
L
L
D
I
L
T
R
S
L
D
L
Frog
Xenopus laevis
Q6DCM9
193
22267
S178
K
G
A
K
S
D
P
S
I
V
R
L
L
Q
C
Zebra Danio
Brachydanio rerio
A9JTH1
193
22206
S178
K
G
A
K
T
D
P
S
I
V
R
L
L
Q
C
Tiger Blowfish
Takifugu rubipres
NP_001027790
189
21769
V168
S
D
D
V
F
M
E
V
M
I
K
S
L
D
L
Fruit Fly
Dros. melanogaster
P42325
190
21875
G172
S
L
E
E
F
I
E
G
A
K
S
D
P
S
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P36609
190
21967
L175
K
E
F
V
D
G
C
L
A
D
K
E
L
F
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
99
93.6
N.A.
91
41.7
N.A.
85.5
80.5
41.2
41.7
61.1
42.2
N.A.
30.8
N.A.
Protein Similarity:
100
94.5
99
97
N.A.
95.5
60.2
N.A.
93.5
90.5
60.2
61.1
75.1
58.7
N.A.
52.7
N.A.
P-Site Identity:
100
20
100
100
N.A.
100
20
N.A.
93.3
80
20
20
33.3
0
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
33.3
N.A.
100
93.3
33.3
33.3
66.6
26.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
0
0
0
0
0
16
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
24
% C
% Asp:
8
54
8
0
8
24
47
8
0
8
0
8
0
54
0
% D
% Glu:
0
8
24
8
0
0
16
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
8
0
16
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
24
0
0
0
8
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
8
24
8
0
8
0
0
8
% I
% Lys:
77
0
0
24
0
0
0
0
0
8
16
0
0
0
0
% K
% Leu:
0
8
8
0
47
47
8
8
54
0
0
24
85
0
54
% L
% Met:
0
0
0
39
0
8
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
24
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
31
0
0
0
0
0
0
0
0
0
0
24
8
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
77
0
0
8
8
% R
% Ser:
16
0
0
0
16
8
0
24
0
0
8
54
0
8
0
% S
% Thr:
0
8
0
8
8
0
0
39
0
54
0
0
0
0
0
% T
% Val:
0
0
0
24
0
0
0
8
0
24
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _