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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCAM
All Species:
22.73
Human Site:
Y641
Identified Species:
50
UniProt:
P43121
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43121
NP_006491.2
646
71607
Y641
P
G
D
Q
G
E
K
Y
I
D
L
R
H
_
_
Chimpanzee
Pan troglodytes
XP_001149681
1230
134039
Y1225
P
G
D
Q
G
E
K
Y
I
D
L
R
H
_
_
Rhesus Macaque
Macaca mulatta
XP_001096935
753
82173
Y748
P
G
D
Q
G
E
K
Y
I
D
L
R
H
_
_
Dog
Lupus familis
XP_546486
813
88440
Y808
P
G
D
Q
G
E
K
Y
I
D
L
R
H
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2Y2
648
71527
Y643
P
G
D
Q
G
E
K
Y
I
D
L
R
H
_
_
Rat
Rattus norvegicus
Q9EPF2
648
71309
Y643
P
G
D
Q
G
E
K
Y
I
D
L
R
H
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517756
394
43137
Chicken
Gallus gallus
P42292
588
65708
E574
D
K
D
L
G
N
I
E
E
N
K
K
L
E
E
Frog
Xenopus laevis
NP_001085893
605
65914
Zebra Danio
Brachydanio rerio
Q90460
564
61255
K554
G
T
S
E
E
S
K
K
L
E
E
N
N
H
K
Tiger Blowfish
Takifugu rubipres
NP_001092127
575
62314
E568
K
L
E
E
K
V
E
E
N
S
Q
K
A
E
V
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.8
81.6
65.4
N.A.
76.2
75.3
N.A.
23.2
25.8
31.8
24.9
25.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
52.2
83.5
69.9
N.A.
87.5
87.3
N.A.
33.1
45.9
48.4
43.3
43
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
13.3
0
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
26.6
0
33.3
26.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
64
0
0
0
0
0
0
55
0
0
0
0
0
% D
% Glu:
0
0
10
19
10
55
10
19
10
10
10
0
0
19
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
55
0
0
64
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
55
10
0
% H
% Ile:
0
0
0
0
0
0
10
0
55
0
0
0
0
0
0
% I
% Lys:
10
10
0
0
10
0
64
10
0
0
10
19
0
0
10
% K
% Leu:
0
10
0
10
0
0
0
0
10
0
55
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
10
0
10
10
0
0
% N
% Pro:
55
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
55
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% R
% Ser:
0
0
10
0
0
10
0
0
0
10
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
55
55
% _