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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRAT All Species: 18.18
Human Site: S253 Identified Species: 30.77
UniProt: P43155 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43155 NP_000746 626 70858 S253 E P V G I L T S N H R N S W A
Chimpanzee Pan troglodytes XP_520305 539 61088 D182 A Y N T L I K D K V N R D S V
Rhesus Macaque Macaca mulatta XP_001109211 626 70697 S253 E P V G I L T S N H R N S W A
Dog Lupus familis XP_548425 626 70878 S253 E P V G I L T S N H R N S W A
Cat Felis silvestris
Mouse Mus musculus P47934 626 70906 S253 E P V G I L T S N H R N T W A
Rat Rattus norvegicus Q704S8 626 70782 S253 E P V G I L T S N H R N S W A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509108 643 72737 L247 E Q L P P I G L L T S D G R A
Chicken Gallus gallus Q90YJ9 640 72605 L244 E M L P P I G L L T T D G R T
Frog Xenopus laevis Q7ZXE1 659 74538 P284 H I L S D N T P T P E F P L G
Zebra Danio Brachydanio rerio B2ZGJ1 637 71821 L239 E R Q P P I G L L T S D G R T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07668 721 81310 E329 R D R E M L Q E D E R N Q R N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P32756 627 71299 W251 R D N A A L F W Q D M L T V E
Sea Urchin Strong. purpuratus XP_001202100 628 70001 A253 V P V G I L T A E H R N T W G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32796 670 77223 K288 Q G S Q S D P K L G G I G S L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.6 97.9 93.1 N.A. 89.9 90.5 N.A. 42.4 41.2 29.7 41.4 N.A. 33.8 N.A. 31.4 49
Protein Similarity: 100 85.4 98.8 96.6 N.A. 95.3 95.8 N.A. 62.6 61 49.9 62.1 N.A. 53.4 N.A. 51.8 66.5
P-Site Identity: 100 0 100 100 N.A. 93.3 100 N.A. 13.3 6.6 6.6 6.6 N.A. 20 N.A. 6.6 66.6
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 33.3 26.6 13.3 20 N.A. 33.3 N.A. 13.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 8 0 0 8 0 0 0 0 0 0 43 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 0 8 8 0 8 8 8 0 22 8 0 0 % D
% Glu: 58 0 0 8 0 0 0 8 8 8 8 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % F
% Gly: 0 8 0 43 0 0 22 0 0 8 8 0 29 0 15 % G
% His: 8 0 0 0 0 0 0 0 0 43 0 0 0 0 0 % H
% Ile: 0 8 0 0 43 29 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 8 8 0 0 0 0 0 0 % K
% Leu: 0 0 22 0 8 58 0 22 29 0 0 8 0 8 8 % L
% Met: 0 8 0 0 8 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 15 0 0 8 0 0 36 0 8 50 0 0 8 % N
% Pro: 0 43 0 22 22 0 8 8 0 8 0 0 8 0 0 % P
% Gln: 8 8 8 8 0 0 8 0 8 0 0 0 8 0 0 % Q
% Arg: 15 8 8 0 0 0 0 0 0 0 50 8 0 29 0 % R
% Ser: 0 0 8 8 8 0 0 36 0 0 15 0 29 15 0 % S
% Thr: 0 0 0 8 0 0 50 0 8 22 8 0 22 0 15 % T
% Val: 8 0 43 0 0 0 0 0 0 8 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 43 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _