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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRAT All Species: 32.12
Human Site: S46 Identified Species: 54.36
UniProt: P43155 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43155 NP_000746 626 70858 S46 P V P P L Q Q S L D H Y L K A
Chimpanzee Pan troglodytes XP_520305 539 61088
Rhesus Macaque Macaca mulatta XP_001109211 626 70697 S46 P V P P L Q Q S L D H Y L K A
Dog Lupus familis XP_548425 626 70878 S46 P V P A L Q Q S L D R Y L K A
Cat Felis silvestris
Mouse Mus musculus P47934 626 70906 S46 P V P P L Q Q S L D Y Y L K A
Rat Rattus norvegicus Q704S8 626 70782 S46 P V P P L Q Q S L D H Y L K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509108 643 72737 I60 Q F R K S K A I V E R F G A P
Chicken Gallus gallus Q90YJ9 640 72605 F51 H L V P E E Q F R K T K S I V
Frog Xenopus laevis Q7ZXE1 659 74538 T62 P I P K F E D T I K R Y L N A
Zebra Danio Brachydanio rerio B2ZGJ1 637 71821 T49 P E D Q F R K T K A V V E K F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07668 721 81310 T99 P V P A L D E T M A D Y I R A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P32756 627 71299 A64 A H K F V R Q A T P L Q E Q L
Sea Urchin Strong. purpuratus XP_001202100 628 70001 T43 P V P P L Q Q T L Y K Y L M A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32796 670 77223 T85 P V P E L K S T L D K Y L Q T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.6 97.9 93.1 N.A. 89.9 90.5 N.A. 42.4 41.2 29.7 41.4 N.A. 33.8 N.A. 31.4 49
Protein Similarity: 100 85.4 98.8 96.6 N.A. 95.3 95.8 N.A. 62.6 61 49.9 62.1 N.A. 53.4 N.A. 51.8 66.5
P-Site Identity: 100 0 100 86.6 N.A. 93.3 100 N.A. 0 13.3 33.3 13.3 N.A. 40 N.A. 6.6 73.3
P-Site Similarity: 100 0 100 86.6 N.A. 100 100 N.A. 26.6 26.6 60 33.3 N.A. 73.3 N.A. 33.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 15 0 0 8 8 0 15 0 0 0 8 58 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 8 8 0 0 43 8 0 0 0 0 % D
% Glu: 0 8 0 8 8 15 8 0 0 8 0 0 15 0 0 % E
% Phe: 0 8 0 8 15 0 0 8 0 0 0 8 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % G
% His: 8 8 0 0 0 0 0 0 0 0 22 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 8 8 0 0 0 8 8 0 % I
% Lys: 0 0 8 15 0 15 8 0 8 15 15 8 0 43 0 % K
% Leu: 0 8 0 0 58 0 0 0 50 0 8 0 58 0 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 72 0 65 43 0 0 0 0 0 8 0 0 0 0 8 % P
% Gln: 8 0 0 8 0 43 58 0 0 0 0 8 0 15 0 % Q
% Arg: 0 0 8 0 0 15 0 0 8 0 22 0 0 8 0 % R
% Ser: 0 0 0 0 8 0 8 36 0 0 0 0 8 0 0 % S
% Thr: 0 0 0 0 0 0 0 36 8 0 8 0 0 0 8 % T
% Val: 0 58 8 0 8 0 0 0 8 0 8 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 8 65 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _