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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLP1R
All Species:
22.42
Human Site:
S431
Identified Species:
61.67
UniProt:
P43220
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43220
NP_002053.3
463
53060
S431
H
L
H
I
Q
R
D
S
S
M
K
P
L
K
C
Chimpanzee
Pan troglodytes
XP_527380
463
53011
S431
H
L
H
I
Q
R
D
S
S
M
K
P
L
K
C
Rhesus Macaque
Macaca mulatta
XP_001117104
474
54049
S442
H
L
H
I
Q
R
D
S
S
M
K
P
L
K
C
Dog
Lupus familis
XP_538899
447
51678
S415
H
L
H
V
Q
R
D
S
S
M
R
P
L
K
C
Cat
Felis silvestris
Mouse
Mus musculus
O35659
489
55860
C431
H
L
N
I
Q
R
D
C
S
M
K
P
L
K
C
Rat
Rattus norvegicus
P32301
463
52858
S431
R
L
N
I
Q
R
D
S
S
M
K
P
L
K
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001129023
459
52529
S427
H
L
Y
V
Q
R
D
S
S
M
K
P
L
K
C
Frog
Xenopus laevis
O42602
415
47768
K384
R
W
H
R
W
Q
D
K
H
S
I
R
A
R
V
Zebra Danio
Brachydanio rerio
XP_693606
508
58211
R417
K
D
I
D
E
E
Y
R
H
T
H
S
Q
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
85.8
86.3
N.A.
85.8
90.9
N.A.
N.A.
76
29.5
47.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
87.9
90.9
N.A.
88.1
94.8
N.A.
N.A.
86.8
49
60.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
78
% C
% Asp:
0
12
0
12
0
0
89
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
12
12
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
67
0
56
0
0
0
0
0
23
0
12
0
0
0
0
% H
% Ile:
0
0
12
56
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
12
0
0
0
0
0
0
12
0
0
67
0
0
78
0
% K
% Leu:
0
78
0
0
0
0
0
0
0
0
0
0
78
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
78
0
0
0
0
0
% M
% Asn:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
78
0
0
12
% P
% Gln:
0
0
0
0
78
12
0
0
0
0
0
0
12
0
0
% Q
% Arg:
23
0
0
12
0
78
0
12
0
0
12
12
0
12
0
% R
% Ser:
0
0
0
0
0
0
0
67
78
12
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
0
% T
% Val:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
12
% V
% Trp:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _