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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSO
All Species:
17.88
Human Site:
S87
Identified Species:
30.26
UniProt:
P43234
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43234
NP_001325.1
321
35958
S87
F
K
A
I
Y
L
R
S
K
P
S
K
F
P
R
Chimpanzee
Pan troglodytes
XP_517502
318
35542
S84
F
K
A
I
Y
L
R
S
K
P
S
K
F
P
R
Rhesus Macaque
Macaca mulatta
XP_001093045
321
35995
S87
F
K
A
I
Y
L
R
S
K
P
S
K
F
P
R
Dog
Lupus familis
XP_539782
518
56900
S282
F
K
A
I
Y
L
R
S
K
P
S
R
S
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM88
312
34705
S78
F
K
A
L
Y
L
G
S
K
Y
A
W
A
P
R
Rat
Rattus norvegicus
P07154
334
37642
N93
E
E
F
R
Q
I
V
N
G
Y
R
H
Q
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510786
301
33355
S70
I
Y
L
R
S
K
T
S
K
L
P
R
Y
S
E
Chicken
Gallus gallus
NP_001026300
320
35009
L86
E
E
F
K
A
I
Y
L
R
S
I
P
Y
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695717
334
36928
A100
F
K
E
Q
Y
L
T
A
R
A
E
A
A
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN93
614
68942
Q373
K
E
R
T
G
L
W
Q
R
D
E
A
K
A
T
Honey Bee
Apis mellifera
XP_623690
374
42365
M134
P
I
R
G
E
K
H
M
N
A
S
Y
H
R
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798313
331
37336
E97
F
S
D
L
T
S
E
E
F
Q
F
Q
Y
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q10716
371
40329
R116
L
G
L
R
K
S
R
R
A
L
L
R
E
L
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43296
368
40400
V114
F
R
K
K
H
L
G
V
R
S
G
F
K
L
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95
51.9
N.A.
71.6
30.2
N.A.
69.1
65.7
N.A.
50.2
N.A.
20.2
34.7
N.A.
40.4
Protein Similarity:
100
99
95.9
55.7
N.A.
80.6
46.7
N.A.
79.1
76
N.A.
66.7
N.A.
32.5
52.9
N.A.
56.8
P-Site Identity:
100
100
100
86.6
N.A.
60
0
N.A.
13.3
0
N.A.
33.3
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
20
N.A.
26.6
26.6
N.A.
53.3
N.A.
20
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
30.4
N.A.
29
N.A.
N.A.
Protein Similarity:
N.A.
46.6
N.A.
47.8
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
36
0
8
0
0
8
8
15
8
15
15
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
15
22
8
0
8
0
8
8
0
0
15
0
8
0
8
% E
% Phe:
58
0
15
0
0
0
0
0
8
0
8
8
22
0
0
% F
% Gly:
0
8
0
8
8
0
15
0
8
0
8
0
0
0
15
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
8
8
0
8
% H
% Ile:
8
8
0
29
0
15
0
0
0
0
8
0
0
0
0
% I
% Lys:
8
43
8
15
8
15
0
0
43
0
0
22
15
15
15
% K
% Leu:
8
0
15
15
0
58
0
8
0
15
8
0
0
22
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
29
8
8
0
43
8
% P
% Gln:
0
0
0
8
8
0
0
8
0
8
0
8
8
0
0
% Q
% Arg:
0
8
15
22
0
0
36
8
29
0
8
22
0
8
36
% R
% Ser:
0
8
0
0
8
15
0
43
0
15
36
0
8
8
0
% S
% Thr:
0
0
0
8
8
0
15
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% W
% Tyr:
0
8
0
0
43
0
8
0
0
15
0
8
22
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _