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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSO
All Species:
8.48
Human Site:
T30
Identified Species:
14.36
UniProt:
P43234
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43234
NP_001325.1
321
35958
T30
A
D
S
R
A
P
F
T
P
T
W
P
R
S
R
Chimpanzee
Pan troglodytes
XP_517502
318
35542
T27
A
D
S
R
A
P
F
T
P
T
W
P
R
S
R
Rhesus Macaque
Macaca mulatta
XP_001093045
321
35995
T30
A
D
S
H
A
P
F
T
P
T
W
Q
R
S
R
Dog
Lupus familis
XP_539782
518
56900
F225
P
G
G
A
V
L
P
F
G
L
A
E
P
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM88
312
34705
V21
C
C
L
G
R
H
G
V
A
G
T
W
S
W
S
Rat
Rattus norvegicus
P07154
334
37642
H36
W
H
Q
W
K
S
T
H
R
R
L
Y
G
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510786
301
33355
V13
S
S
S
S
L
H
I
V
L
Q
P
H
I
G
A
Chicken
Gallus gallus
NP_001026300
320
35009
A29
F
A
V
P
A
G
A
A
G
R
P
P
W
D
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695717
334
36928
Q43
L
Q
H
S
D
T
F
Q
Q
D
V
N
N
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VN93
614
68942
G316
Y
K
F
Q
V
R
F
G
R
R
Y
V
S
T
A
Honey Bee
Apis mellifera
XP_623690
374
42365
E77
N
N
P
S
E
Y
E
E
R
F
K
R
F
Q
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798313
331
37336
I40
L
E
E
S
F
F
Q
I
F
I
Q
K
F
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q10716
371
40329
Y59
V
Q
R
F
G
K
S
Y
K
D
A
D
E
H
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43296
368
40400
K57
H
F
S
L
F
K
R
K
F
G
K
V
Y
A
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95
51.9
N.A.
71.6
30.2
N.A.
69.1
65.7
N.A.
50.2
N.A.
20.2
34.7
N.A.
40.4
Protein Similarity:
100
99
95.9
55.7
N.A.
80.6
46.7
N.A.
79.1
76
N.A.
66.7
N.A.
32.5
52.9
N.A.
56.8
P-Site Identity:
100
100
86.6
0
N.A.
0
0
N.A.
6.6
13.3
N.A.
6.6
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
86.6
0
N.A.
0
6.6
N.A.
13.3
13.3
N.A.
6.6
N.A.
26.6
13.3
N.A.
20
Percent
Protein Identity:
N.A.
30.4
N.A.
29
N.A.
N.A.
Protein Similarity:
N.A.
46.6
N.A.
47.8
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
0
8
29
0
8
8
8
0
15
0
0
8
22
% A
% Cys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
22
0
0
8
0
0
0
0
15
0
8
0
8
0
% D
% Glu:
0
8
8
0
8
0
8
8
0
0
0
8
8
8
0
% E
% Phe:
8
8
8
8
15
8
36
8
15
8
0
0
15
0
0
% F
% Gly:
0
8
8
8
8
8
8
8
15
15
0
0
8
15
8
% G
% His:
8
8
8
8
0
15
0
8
0
0
0
8
0
8
0
% H
% Ile:
0
0
0
0
0
0
8
8
0
8
0
0
8
0
0
% I
% Lys:
0
8
0
0
8
15
0
8
8
0
15
8
0
0
8
% K
% Leu:
15
0
8
8
8
8
0
0
8
8
8
0
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
0
0
0
8
8
8
8
% N
% Pro:
8
0
8
8
0
22
8
0
22
0
15
22
8
0
0
% P
% Gln:
0
15
8
8
0
0
8
8
8
8
8
8
0
8
0
% Q
% Arg:
0
0
8
15
8
8
8
0
22
22
0
8
22
0
29
% R
% Ser:
8
8
36
29
0
8
8
0
0
0
0
0
15
22
15
% S
% Thr:
0
0
0
0
0
8
8
22
0
22
8
0
0
15
0
% T
% Val:
8
0
8
0
15
0
0
15
0
0
8
15
0
0
0
% V
% Trp:
8
0
0
8
0
0
0
0
0
0
22
8
8
8
0
% W
% Tyr:
8
0
0
0
0
8
0
8
0
0
8
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _