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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSK
All Species:
24.24
Human Site:
S45
Identified Species:
59.26
UniProt:
P43235
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43235
NP_000387.1
329
36966
S45
N
N
K
V
D
E
I
S
R
R
L
I
W
E
K
Chimpanzee
Pan troglodytes
XP_513780
329
36946
S45
N
N
K
V
D
E
I
S
R
R
L
I
W
E
K
Rhesus Macaque
Macaca mulatta
NP_001027984
329
36923
S45
N
S
K
V
D
E
I
S
R
R
L
I
W
E
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P55097
329
36870
S45
N
S
K
V
D
E
I
S
R
R
L
I
W
E
K
Rat
Rattus norvegicus
O35186
329
36772
S45
N
S
K
V
D
E
I
S
R
R
L
I
W
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518002
618
66856
S334
N
S
K
E
D
E
T
S
R
R
L
V
W
E
K
Chicken
Gallus gallus
Q90686
334
37200
V50
Q
R
Q
G
G
R
N
V
P
E
V
D
L
G
E
Frog
Xenopus laevis
NP_001106314
331
37286
Q47
N
G
Q
M
D
E
L
Q
R
R
L
I
W
E
K
Zebra Danio
Brachydanio rerio
NP_001017778
333
36984
S48
Y
N
G
L
N
E
E
S
I
R
R
T
I
W
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95029
371
41582
N86
R
L
K
I
F
N
E
N
K
H
K
I
A
K
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.4
N.A.
N.A.
86
87.5
N.A.
44.6
68.8
67
61.5
N.A.
42.3
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.6
N.A.
N.A.
92
92
N.A.
49.3
79.6
82.4
76.5
N.A.
58.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
N.A.
N.A.
93.3
93.3
N.A.
73.3
0
66.6
26.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
86.6
20
86.6
46.6
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
70
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
10
0
80
20
0
0
10
0
0
0
70
20
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
10
10
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% H
% Ile:
0
0
0
10
0
0
50
0
10
0
0
70
10
0
0
% I
% Lys:
0
0
70
0
0
0
0
0
10
0
10
0
0
10
70
% K
% Leu:
0
10
0
10
0
0
10
0
0
0
70
0
10
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
70
30
0
0
10
10
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
10
0
20
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
0
10
0
0
70
80
10
0
0
0
0
% R
% Ser:
0
40
0
0
0
0
0
70
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
50
0
0
0
10
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
70
10
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _