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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPD2 All Species: 34.55
Human Site: S191 Identified Species: 50.67
UniProt: P43304 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43304 NP_000399.2 727 80853 S191 A G S N C L K S S Y V L S K S
Chimpanzee Pan troglodytes XP_001142893 693 77234 Y185 L V G A I V Y Y D G Q H N D A
Rhesus Macaque Macaca mulatta XP_001086947 727 80814 S191 A G S N C L K S S Y V L S K S
Dog Lupus familis XP_848389 736 81958 S191 A G S N C L K S S Y V L S K S
Cat Felis silvestris
Mouse Mus musculus Q64521 727 80935 S191 A G S Q C L K S S Y V L S K S
Rat Rattus norvegicus P35571 727 80954 S191 A G S H C L K S S Y V L S K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509091 727 80780 S191 A G T Q C L K S S Y I L S K S
Chicken Gallus gallus XP_422168 727 80733 R191 A G S Q C L K R S Y V L S K S
Frog Xenopus laevis NP_001086009 725 80597 S189 A G S Q C L R S S Y I L S K S
Zebra Danio Brachydanio rerio NP_001038813 536 58932 L36 Y R K N Q A R L A Y V E A Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611063 724 80404 S185 A G D R N V K S S Y Y L S K K
Honey Bee Apis mellifera XP_624293 720 80348 S186 V K S S Y F L S K R N A L E L
Nematode Worm Caenorhab. elegans P90795 722 80789 N196 S G K R V L K N S F F I N K S
Sea Urchin Strong. purpuratus XP_782036 720 80442 S191 A G R Q N L R S S Y F L S K E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SS48 629 68433 A129 G V R Y L E K A V F N L D Y G
Baker's Yeast Sacchar. cerevisiae P32191 649 72370 A149 R K H L I N T A P H L C T V L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 99.1 91.9 N.A. 93.2 91.6 N.A. 90.5 82.9 82.8 61 N.A. 60.9 61.6 57.7 62.8
Protein Similarity: 100 95.3 99.7 94.2 N.A. 97.1 96.4 N.A. 95.7 92.4 91.3 67.4 N.A. 76.3 77.7 74.8 77.8
P-Site Identity: 100 0 100 100 N.A. 93.3 93.3 N.A. 80 86.6 80 20 N.A. 60 13.3 40 60
P-Site Similarity: 100 20 100 100 N.A. 93.3 100 N.A. 93.3 86.6 93.3 46.6 N.A. 66.6 26.6 73.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. 41.4 29 N.A.
Protein Similarity: N.A. N.A. N.A. 54.8 46.2 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 63 0 0 7 0 7 0 13 7 0 0 7 7 0 7 % A
% Cys: 0 0 0 0 50 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 7 0 0 0 0 0 7 0 0 0 7 7 0 % D
% Glu: 0 0 0 0 0 7 0 0 0 0 0 7 0 7 7 % E
% Phe: 0 0 0 0 0 7 0 0 0 13 13 0 0 0 0 % F
% Gly: 7 69 7 0 0 0 0 0 0 7 0 0 0 0 13 % G
% His: 0 0 7 7 0 0 0 0 0 7 0 7 0 0 0 % H
% Ile: 0 0 0 0 13 0 0 0 0 0 13 7 0 0 0 % I
% Lys: 0 13 13 0 0 0 63 0 7 0 0 0 0 69 7 % K
% Leu: 7 0 0 7 7 63 7 7 0 0 7 69 7 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 25 13 7 0 7 0 0 13 0 13 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % P
% Gln: 0 0 0 32 7 0 0 0 0 0 7 0 0 7 0 % Q
% Arg: 7 7 13 13 0 0 19 7 0 7 0 0 0 0 0 % R
% Ser: 7 0 50 7 0 0 0 63 69 0 0 0 63 0 57 % S
% Thr: 0 0 7 0 0 0 7 0 0 0 0 0 7 0 0 % T
% Val: 7 13 0 0 7 13 0 0 7 0 44 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 7 7 0 7 7 0 69 7 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _