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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRYBB2
All Species:
17.27
Human Site:
S174
Identified Species:
42.22
UniProt:
P43320
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43320
NP_000487.1
205
23380
S174
E
K
G
D
Y
K
D
S
S
D
F
G
A
P
H
Chimpanzee
Pan troglodytes
XP_520649
392
44728
S361
E
K
G
D
Y
K
D
S
S
D
F
G
A
P
H
Rhesus Macaque
Macaca mulatta
A3RLD8
174
20712
R147
R
G
R
Q
Y
L
L
R
P
Q
E
Y
R
R
C
Dog
Lupus familis
XP_543459
248
27747
W212
E
P
G
D
F
R
H
W
N
E
W
G
A
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJU9
211
24273
W181
E
R
G
E
F
R
H
W
N
E
W
D
A
N
Q
Rat
Rattus norvegicus
P62697
205
23362
N174
E
K
G
D
Y
K
D
N
S
D
F
G
A
P
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509294
205
23392
S174
E
K
G
E
Y
K
D
S
A
E
F
G
A
Q
H
Chicken
Gallus gallus
Q05714
219
25041
S188
E
K
G
D
Y
K
D
S
S
E
F
G
A
Q
H
Frog
Xenopus laevis
NP_001086491
204
23554
S173
E
K
G
D
Y
K
D
S
S
D
F
G
A
Q
H
Zebra Danio
Brachydanio rerio
Q6DGY7
183
21727
E156
R
G
R
M
Y
I
V
E
R
G
N
Y
C
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
31.2
48.3
N.A.
53.5
97
N.A.
82.9
77.6
81.9
33.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
51.7
49.7
62.5
N.A.
75.3
99.5
N.A.
91.7
85.8
91.2
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
33.3
N.A.
20
93.3
N.A.
73.3
86.6
93.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
66.6
N.A.
66.6
100
N.A.
93.3
93.3
93.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
80
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% C
% Asp:
0
0
0
60
0
0
60
0
0
40
0
10
0
0
0
% D
% Glu:
80
0
0
20
0
0
0
10
0
40
10
0
0
0
0
% E
% Phe:
0
0
0
0
20
0
0
0
0
0
60
0
0
10
0
% F
% Gly:
0
20
80
0
0
0
0
0
0
10
0
70
0
10
0
% G
% His:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
70
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
60
0
0
0
60
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
20
0
10
0
0
10
0
% N
% Pro:
0
10
0
0
0
0
0
0
10
0
0
0
0
30
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
10
0
0
0
30
20
% Q
% Arg:
20
10
20
0
0
20
0
10
10
0
0
0
10
10
0
% R
% Ser:
0
0
0
0
0
0
0
50
50
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
20
0
0
20
0
0
0
0
% W
% Tyr:
0
0
0
0
80
0
0
0
0
0
0
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _