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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRYBB2 All Species: 14.24
Human Site: S95 Identified Species: 34.81
UniProt: P43320 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43320 NP_000487.1 205 23380 S95 S R R T D S L S S L R P I K V
Chimpanzee Pan troglodytes XP_520649 392 44728 S282 S R R T D S L S S L R P I K V
Rhesus Macaque Macaca mulatta A3RLD8 174 20712 Q68 G E Y P D Y Q Q W M G L S D S
Dog Lupus familis XP_543459 248 27747 M133 S Y R S D R L M S F R P I K M
Cat Felis silvestris
Mouse Mus musculus Q9JJU9 211 24273 L102 S R R S D I L L S L R P L H I
Rat Rattus norvegicus P62697 205 23362 S95 S R R T D S L S S L R P I K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509294 205 23392 G95 S R R S D C I G S L R P V K V
Chicken Gallus gallus Q05714 219 25041 P109 V V R A P R Q P L P T R Q T K
Frog Xenopus laevis NP_001086491 204 23554 S94 N R R T D S I S S M R P I K I
Zebra Danio Brachydanio rerio Q6DGY7 183 21727 S77 P E F Q R W N S H N D H M G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.2 31.2 48.3 N.A. 53.5 97 N.A. 82.9 77.6 81.9 33.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 51.7 49.7 62.5 N.A. 75.3 99.5 N.A. 91.7 85.8 91.2 57 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 60 N.A. 60 100 N.A. 66.6 6.6 73.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 73.3 N.A. 80 100 N.A. 86.6 6.6 100 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 80 0 0 0 0 0 10 0 0 10 0 % D
% Glu: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 10 0 0 10 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 10 0 10 0 % H
% Ile: 0 0 0 0 0 10 20 0 0 0 0 0 50 0 20 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 60 10 % K
% Leu: 0 0 0 0 0 0 50 10 10 50 0 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 20 0 0 10 0 10 % M
% Asn: 10 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % N
% Pro: 10 0 0 10 10 0 0 10 0 10 0 70 0 0 0 % P
% Gln: 0 0 0 10 0 0 20 10 0 0 0 0 10 0 0 % Q
% Arg: 0 60 80 0 10 20 0 0 0 0 70 10 0 0 0 % R
% Ser: 60 0 0 30 0 40 0 50 70 0 0 0 10 0 20 % S
% Thr: 0 0 0 40 0 0 0 0 0 0 10 0 0 10 0 % T
% Val: 10 10 0 0 0 0 0 0 0 0 0 0 10 0 40 % V
% Trp: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 10 10 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _