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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAD52 All Species: 9.39
Human Site: S299 Identified Species: 22.96
UniProt: P43351 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43351 NP_602296.2 418 46169 S299 P A P P V T H S T P V T V S E
Chimpanzee Pan troglodytes XP_001150943 418 46083 S299 P A P P L T H S T P V T V S E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534926 393 43481 E275 L Q Q K F R E E M E K Q Q Q A
Cat Felis silvestris
Mouse Mus musculus P43352 420 46891 H298 A E E V A A K H A A V L P A P
Rat Rattus norvegicus NP_001100087 427 47122 L305 P P P H S A A L P A P P K H S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P39022 422 47704 S303 A N P P V K H S T P A A V Q Q
Frog Xenopus laevis NP_001089585 429 48071 P310 T A Y P A R V P P L G H S T P
Zebra Danio Brachydanio rerio NP_001019622 409 45818 L291 D S K Q Q R K L R Q Q Q L Q Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P06778 471 52385 T353 I R H T V D Q T T S K H I P A
Red Bread Mold Neurospora crassa Q9HGI2 600 63476 S402 N P H A E S P S I R K T P G I
Conservation
Percent
Protein Identity: 100 96.4 N.A. 68.9 N.A. 70.2 65.8 N.A. N.A. 53.5 54.5 44.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.8 N.A. 76.7 N.A. 79.2 74 N.A. N.A. 65.6 68.5 59.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 N.A. 0 N.A. 6.6 13.3 N.A. N.A. 53.3 13.3 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 0 N.A. 13.3 13.3 N.A. N.A. 60 20 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.8 28
Protein Similarity: N.A. N.A. N.A. N.A. 45.4 39.1
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 30 0 10 20 20 10 0 10 20 10 10 0 10 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 10 0 10 0 10 10 0 10 0 0 0 0 20 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % G
% His: 0 0 20 10 0 0 30 10 0 0 0 20 0 10 0 % H
% Ile: 10 0 0 0 0 0 0 0 10 0 0 0 10 0 10 % I
% Lys: 0 0 10 10 0 10 20 0 0 0 30 0 10 0 0 % K
% Leu: 10 0 0 0 10 0 0 20 0 10 0 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 30 20 40 40 0 0 10 10 20 30 10 10 20 10 20 % P
% Gln: 0 10 10 10 10 0 10 0 0 10 10 20 10 30 20 % Q
% Arg: 0 10 0 0 0 30 0 0 10 10 0 0 0 0 0 % R
% Ser: 0 10 0 0 10 10 0 40 0 10 0 0 10 20 10 % S
% Thr: 10 0 0 10 0 20 0 10 40 0 0 30 0 10 0 % T
% Val: 0 0 0 10 30 0 10 0 0 0 30 0 30 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _