Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZAP70 All Species: 13.33
Human Site: T588 Identified Species: 26.67
UniProt: P43403 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43403 NP_001070.2 619 69872 T588 E D R P D F L T V E Q R M R A
Chimpanzee Pan troglodytes XP_515637 619 69840 T588 E D R P D F L T V E Q R M R A
Rhesus Macaque Macaca mulatta XP_001101570 619 69877 T588 E D R P D F L T V E Q R M R A
Dog Lupus familis XP_861301 601 68596 E566 C P A G C P R E M Y E L M K L
Cat Felis silvestris
Mouse Mus musculus P43404 618 70040 T587 E D R P D F L T V E Q R M R N
Rat Rattus norvegicus Q64725 629 71510 M595 P P G C P R E M Y D L M F L C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515271 507 56102 V477 Q L D N P Y I V R I I G V C R
Chicken Gallus gallus Q07494 984 109166 E873 N T R P R L A E I V N T L D K
Frog Xenopus laevis Q91736 902 100832 E791 N S R P R F G E I V N T L D K
Zebra Danio Brachydanio rerio O13146 981 109636 Q878 S D R P K F G Q I V N T L D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24145 939 104255 R907 M Q S C W K E R P K D R P T F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189062 746 84636 L711 S L M R R C W L S E A K D R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.5 53.6 N.A. 93.5 53.7 N.A. 57.6 22.6 24.2 25.2 N.A. 25.1 N.A. N.A. 34
Protein Similarity: 100 100 98.3 70.4 N.A. 96.1 70.9 N.A. 62.6 35.5 39.1 37.4 N.A. 40.8 N.A. N.A. 49.4
P-Site Identity: 100 100 100 6.6 N.A. 93.3 0 N.A. 0 13.3 20 26.6 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 26.6 N.A. 93.3 6.6 N.A. 26.6 26.6 33.3 40 N.A. 13.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 9 0 0 0 9 0 0 0 25 % A
% Cys: 9 0 0 17 9 9 0 0 0 0 0 0 0 9 9 % C
% Asp: 0 42 9 0 34 0 0 0 0 9 9 0 9 25 0 % D
% Glu: 34 0 0 0 0 0 17 25 0 42 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 50 0 0 0 0 0 0 9 0 9 % F
% Gly: 0 0 9 9 0 0 17 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 25 9 9 0 0 0 0 % I
% Lys: 0 0 0 0 9 9 0 0 0 9 0 9 0 9 17 % K
% Leu: 0 17 0 0 0 9 34 9 0 0 9 9 25 9 9 % L
% Met: 9 0 9 0 0 0 0 9 9 0 0 9 42 0 0 % M
% Asn: 17 0 0 9 0 0 0 0 0 0 25 0 0 0 9 % N
% Pro: 9 17 0 59 17 9 0 0 9 0 0 0 9 0 9 % P
% Gln: 9 9 0 0 0 0 0 9 0 0 34 0 0 0 0 % Q
% Arg: 0 0 59 9 25 9 9 9 9 0 0 42 0 42 17 % R
% Ser: 17 9 9 0 0 0 0 0 9 0 0 0 0 0 0 % S
% Thr: 0 9 0 0 0 0 0 34 0 0 0 25 0 9 0 % T
% Val: 0 0 0 0 0 0 0 9 34 25 0 0 9 0 0 % V
% Trp: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 9 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _