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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZAP70
All Species:
14.55
Human Site:
Y569
Identified Species:
29.09
UniProt:
P43403
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43403
NP_001070.2
619
69872
Y569
P
E
C
P
P
E
L
Y
A
L
M
S
D
C
W
Chimpanzee
Pan troglodytes
XP_515637
619
69840
Y569
P
E
C
P
P
E
L
Y
A
L
M
S
D
C
W
Rhesus Macaque
Macaca mulatta
XP_001101570
619
69877
Y569
S
E
C
P
P
E
L
Y
E
L
M
S
D
C
W
Dog
Lupus familis
XP_861301
601
68596
V547
R
G
M
K
G
S
E
V
S
A
M
L
E
K
G
Cat
Felis silvestris
Mouse
Mus musculus
P43404
618
70040
Y568
P
E
C
P
P
E
M
Y
A
L
M
S
D
C
W
Rat
Rattus norvegicus
Q64725
629
71510
T576
G
M
K
G
S
E
V
T
A
M
L
E
K
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515271
507
56102
K458
S
G
N
E
K
A
E
K
E
E
M
M
K
E
A
Chicken
Gallus gallus
Q07494
984
109166
H854
M
D
C
P
A
A
L
H
Q
L
M
L
D
C
W
Frog
Xenopus laevis
Q91736
902
100832
H772
M
D
C
P
A
A
L
H
Q
L
M
L
D
C
W
Zebra Danio
Brachydanio rerio
O13146
981
109636
H859
M
D
C
P
V
V
L
H
Q
L
M
L
D
C
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24145
939
104255
Q888
D
S
G
E
R
L
P
Q
P
N
L
C
P
A
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189062
746
84636
L692
F
I
E
N
G
D
R
L
S
Q
P
D
R
C
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
53.6
N.A.
93.5
53.7
N.A.
57.6
22.6
24.2
25.2
N.A.
25.1
N.A.
N.A.
34
Protein Similarity:
100
100
98.3
70.4
N.A.
96.1
70.9
N.A.
62.6
35.5
39.1
37.4
N.A.
40.8
N.A.
N.A.
49.4
P-Site Identity:
100
100
86.6
6.6
N.A.
93.3
13.3
N.A.
6.6
53.3
53.3
53.3
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
86.6
20
N.A.
100
33.3
N.A.
6.6
66.6
66.6
66.6
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
25
0
0
34
9
0
0
0
9
9
% A
% Cys:
0
0
59
0
0
0
0
0
0
0
0
9
0
67
0
% C
% Asp:
9
25
0
0
0
9
0
0
0
0
0
9
59
0
0
% D
% Glu:
0
34
9
17
0
42
17
0
17
9
0
9
9
9
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
17
9
9
17
0
0
0
0
0
0
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
9
9
0
0
9
0
0
0
0
17
9
0
% K
% Leu:
0
0
0
0
0
9
50
9
0
59
17
34
0
0
0
% L
% Met:
25
9
9
0
0
0
9
0
0
9
75
9
0
0
0
% M
% Asn:
0
0
9
9
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
25
0
0
59
34
0
9
0
9
0
9
0
9
0
9
% P
% Gln:
0
0
0
0
0
0
0
9
25
9
0
0
0
0
0
% Q
% Arg:
9
0
0
0
9
0
9
0
0
0
0
0
9
0
0
% R
% Ser:
17
9
0
0
9
9
0
0
17
0
0
34
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
9
9
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _