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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFRSF4
All Species:
10.56
Human Site:
S272
Identified Species:
46.46
UniProt:
P43489
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43489
NP_003318.1
277
29341
S272
E
E
Q
A
D
A
H
S
T
L
A
K
I
_
_
Chimpanzee
Pan troglodytes
XP_513705
276
28743
S271
E
E
Q
A
D
A
H
S
T
L
A
K
I
_
_
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546720
264
28555
S259
E
E
H
A
D
A
N
S
T
L
A
K
I
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P47741
272
30135
F267
E
E
H
T
D
A
H
F
T
L
A
K
I
_
_
Rat
Rattus norvegicus
P15725
271
29877
F266
E
E
Q
T
D
T
H
F
T
L
A
K
I
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18519
416
44636
Y407
G
D
I
A
E
S
L
Y
S
E
S
T
A
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
N.A.
62
N.A.
62.8
62
N.A.
N.A.
21.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
84.1
N.A.
70.4
N.A.
70.7
69.3
N.A.
N.A.
34.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
84.6
N.A.
76.9
76.9
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
92.3
N.A.
76.9
76.9
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
67
0
67
0
0
0
0
84
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
84
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
84
84
0
0
17
0
0
0
0
17
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
34
0
0
0
67
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
17
0
0
0
0
0
0
0
0
0
84
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
84
0
0
0
% K
% Leu:
0
0
0
0
0
0
17
0
0
84
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
17
0
50
17
0
17
0
0
0
17
% S
% Thr:
0
0
0
34
0
17
0
0
84
0
0
17
0
17
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
84
84
% _