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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAMPT
All Species:
25.45
Human Site:
Y453
Identified Species:
70
UniProt:
P43490
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43490
NP_005737.1
491
55521
Y453
G
K
G
D
L
E
E
Y
G
Q
D
L
L
H
T
Chimpanzee
Pan troglodytes
XP_519302
491
55517
Y453
G
K
G
D
L
E
E
Y
G
Q
D
L
L
H
T
Rhesus Macaque
Macaca mulatta
XP_001090562
490
55124
Y452
G
K
G
D
L
E
E
Y
G
H
D
L
L
H
T
Dog
Lupus familis
XP_540386
588
66002
Y550
G
K
G
D
L
E
E
Y
G
H
D
L
L
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99KQ4
491
55428
Y453
G
K
G
D
L
E
E
Y
G
H
D
L
L
H
T
Rat
Rattus norvegicus
Q80Z29
491
55419
Y453
G
K
G
D
L
E
E
Y
G
H
D
L
L
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509090
538
60620
C499
G
K
G
D
L
E
E
C
G
H
D
L
L
H
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082484
491
56022
Y452
G
K
G
D
L
E
E
Y
G
P
D
L
L
R
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782393
480
53754
P439
I
E
E
G
K
G
D
P
N
K
N
L
L
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
93.8
78.4
N.A.
95.7
95.1
N.A.
82.7
N.A.
86.5
N.A.
N.A.
N.A.
N.A.
N.A.
56.6
Protein Similarity:
100
100
96.9
81.4
N.A.
98.3
98.1
N.A.
87.5
N.A.
93
N.A.
N.A.
N.A.
N.A.
N.A.
73.9
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
89
0
0
12
0
0
0
89
0
0
0
0
% D
% Glu:
0
12
12
0
0
89
89
0
0
0
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
89
0
89
12
0
12
0
0
89
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
56
0
0
0
78
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
89
0
0
12
0
0
0
0
12
0
0
0
0
0
% K
% Leu:
0
0
0
0
89
0
0
0
0
0
0
100
100
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
12
0
12
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
89
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
78
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _