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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AFM
All Species:
11.21
Human Site:
Y212
Identified Species:
30.83
UniProt:
P43652
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43652
NP_001124.1
599
69069
Y212
R
A
I
P
V
T
Q
Y
L
K
A
F
S
S
Y
Chimpanzee
Pan troglodytes
Q28789
609
68723
E212
K
A
A
T
V
T
K
E
L
R
E
S
S
L
L
Rhesus Macaque
Macaca mulatta
Q28522
600
67862
E204
K
L
D
E
L
R
D
E
G
K
A
S
S
A
K
Dog
Lupus familis
XP_532408
604
69080
Y212
K
A
E
L
V
I
Q
Y
L
K
A
S
S
S
F
Cat
Felis silvestris
Mouse
Mus musculus
O89020
608
69361
Y212
K
A
A
P
I
T
Q
Y
L
K
A
S
S
S
Y
Rat
Rattus norvegicus
P36953
608
69317
Y212
K
A
A
P
I
T
Q
Y
L
K
A
L
S
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511450
602
69140
D209
K
G
T
L
V
T
N
D
L
R
W
I
H
E
I
Chicken
Gallus gallus
P19121
615
69900
K216
K
E
I
V
M
R
E
K
A
K
G
V
S
V
K
Frog
Xenopus laevis
P14872
607
70364
Q211
K
M
K
Q
L
M
K
Q
S
H
S
I
E
D
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.2
34.6
74.3
N.A.
66.7
66.7
N.A.
40.5
38.8
28.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
60.2
54
86.2
N.A.
79.4
79.6
N.A.
63.6
58.2
50
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
20
60
N.A.
73.3
73.3
N.A.
20
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
40
73.3
N.A.
86.6
86.6
N.A.
33.3
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
56
34
0
0
0
0
0
12
0
56
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
12
12
0
0
0
0
0
12
0
% D
% Glu:
0
12
12
12
0
0
12
23
0
0
12
0
12
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% F
% Gly:
0
12
0
0
0
0
0
0
12
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% H
% Ile:
0
0
23
0
23
12
0
0
0
0
0
23
0
0
12
% I
% Lys:
89
0
12
0
0
0
23
12
0
67
0
0
0
0
34
% K
% Leu:
0
12
0
23
23
0
0
0
67
0
0
12
0
12
12
% L
% Met:
0
12
0
0
12
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
12
0
0
45
12
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
23
0
0
0
23
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
12
0
12
45
78
45
0
% S
% Thr:
0
0
12
12
0
56
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
45
0
0
0
0
0
0
12
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
45
0
0
0
0
0
0
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _