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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC4
All Species:
35.15
Human Site:
S156
Identified Species:
48.33
UniProt:
P43686
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43686
NP_006494.1
418
47366
S156
S
S
I
M
M
L
T
S
D
Q
K
P
D
V
M
Chimpanzee
Pan troglodytes
XP_001141067
422
47807
S156
S
S
I
M
M
L
T
S
D
Q
K
P
D
V
M
Rhesus Macaque
Macaca mulatta
XP_001090437
422
47818
S156
S
S
I
M
M
L
T
S
D
Q
K
P
D
V
M
Dog
Lupus familis
XP_867041
419
47479
S156
S
S
I
M
M
L
T
S
D
Q
K
P
D
V
M
Cat
Felis silvestris
Mouse
Mus musculus
P54775
418
47263
S156
S
S
I
M
M
L
T
S
D
Q
K
P
D
V
M
Rat
Rattus norvegicus
Q63570
418
47390
S156
S
S
I
M
M
L
T
S
D
Q
K
P
D
V
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518401
484
54060
S258
S
S
I
M
M
L
T
S
D
Q
K
P
D
V
M
Chicken
Gallus gallus
Q90732
440
49185
L176
P
L
V
T
V
M
K
L
E
K
A
P
Q
E
T
Frog
Xenopus laevis
NP_001083300
420
47373
A158
S
S
I
T
M
L
T
A
D
Q
K
P
D
V
L
Zebra Danio
Brachydanio rerio
NP_956044
418
47242
S156
S
S
I
M
M
L
T
S
D
Q
K
P
D
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
L175
P
M
V
T
V
M
K
L
E
K
A
P
Q
E
T
Honey Bee
Apis mellifera
XP_393513
415
47021
A153
S
S
I
S
M
L
Q
A
D
E
K
P
D
I
Q
Nematode Worm
Caenorhab. elegans
P46502
414
46340
P152
S
S
I
Q
M
L
R
P
D
E
K
P
D
I
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002322593
412
46473
Q150
S
S
I
S
L
L
S
Q
S
E
K
P
D
V
T
Maize
Zea mays
NP_001150600
420
46705
S158
S
S
I
S
L
L
G
S
S
E
K
P
N
V
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEI4
408
45733
Q146
S
S
I
S
L
L
S
Q
S
E
K
P
D
V
S
Baker's Yeast
Sacchar. cerevisiae
P33298
428
47951
E163
S
S
I
S
V
M
G
E
N
E
K
P
D
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99
99.5
N.A.
97.8
99.7
N.A.
73.9
45.2
95.9
96.6
N.A.
46
85.4
76.7
N.A.
Protein Similarity:
100
99
99
99.7
N.A.
98.3
99.7
N.A.
77.2
68.1
97.6
98.5
N.A.
70.1
92.5
85.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
6.6
80
93.3
N.A.
6.6
60
60
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
40
93.3
100
N.A.
40
80
73.3
N.A.
Percent
Protein Identity:
77.7
77.1
N.A.
77
67.2
N.A.
Protein Similarity:
87.3
85.7
N.A.
85.8
81.7
N.A.
P-Site Identity:
53.3
53.3
N.A.
53.3
46.6
N.A.
P-Site Similarity:
73.3
73.3
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
65
0
0
0
83
0
0
% D
% Glu:
0
0
0
0
0
0
0
6
12
36
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
89
0
0
0
0
0
0
0
0
0
0
12
0
% I
% Lys:
0
0
0
0
0
0
12
0
0
12
89
0
0
0
0
% K
% Leu:
0
6
0
0
18
83
0
12
0
0
0
0
0
0
12
% L
% Met:
0
6
0
48
65
18
0
0
0
0
0
0
0
0
42
% M
% Asn:
0
0
0
0
0
0
0
0
6
0
0
0
6
0
0
% N
% Pro:
12
0
0
0
0
0
0
6
0
0
0
100
0
0
0
% P
% Gln:
0
0
0
6
0
0
6
12
0
53
0
0
12
0
6
% Q
% Arg:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% R
% Ser:
89
89
0
30
0
0
12
53
18
0
0
0
0
0
12
% S
% Thr:
0
0
0
18
0
0
53
0
0
0
0
0
0
0
30
% T
% Val:
0
0
12
0
18
0
0
0
0
0
0
0
0
77
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _