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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC4 All Species: 35.15
Human Site: S156 Identified Species: 48.33
UniProt: P43686 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43686 NP_006494.1 418 47366 S156 S S I M M L T S D Q K P D V M
Chimpanzee Pan troglodytes XP_001141067 422 47807 S156 S S I M M L T S D Q K P D V M
Rhesus Macaque Macaca mulatta XP_001090437 422 47818 S156 S S I M M L T S D Q K P D V M
Dog Lupus familis XP_867041 419 47479 S156 S S I M M L T S D Q K P D V M
Cat Felis silvestris
Mouse Mus musculus P54775 418 47263 S156 S S I M M L T S D Q K P D V M
Rat Rattus norvegicus Q63570 418 47390 S156 S S I M M L T S D Q K P D V M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518401 484 54060 S258 S S I M M L T S D Q K P D V M
Chicken Gallus gallus Q90732 440 49185 L176 P L V T V M K L E K A P Q E T
Frog Xenopus laevis NP_001083300 420 47373 A158 S S I T M L T A D Q K P D V L
Zebra Danio Brachydanio rerio NP_956044 418 47242 S156 S S I M M L T S D Q K P D V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48601 439 49305 L175 P M V T V M K L E K A P Q E T
Honey Bee Apis mellifera XP_393513 415 47021 A153 S S I S M L Q A D E K P D I Q
Nematode Worm Caenorhab. elegans P46502 414 46340 P152 S S I Q M L R P D E K P D I S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002322593 412 46473 Q150 S S I S L L S Q S E K P D V T
Maize Zea mays NP_001150600 420 46705 S158 S S I S L L G S S E K P N V T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEI4 408 45733 Q146 S S I S L L S Q S E K P D V S
Baker's Yeast Sacchar. cerevisiae P33298 428 47951 E163 S S I S V M G E N E K P D V T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 99 99.5 N.A. 97.8 99.7 N.A. 73.9 45.2 95.9 96.6 N.A. 46 85.4 76.7 N.A.
Protein Similarity: 100 99 99 99.7 N.A. 98.3 99.7 N.A. 77.2 68.1 97.6 98.5 N.A. 70.1 92.5 85.4 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 6.6 80 93.3 N.A. 6.6 60 60 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 40 93.3 100 N.A. 40 80 73.3 N.A.
Percent
Protein Identity: 77.7 77.1 N.A. 77 67.2 N.A.
Protein Similarity: 87.3 85.7 N.A. 85.8 81.7 N.A.
P-Site Identity: 53.3 53.3 N.A. 53.3 46.6 N.A.
P-Site Similarity: 73.3 73.3 N.A. 73.3 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 0 0 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 65 0 0 0 83 0 0 % D
% Glu: 0 0 0 0 0 0 0 6 12 36 0 0 0 12 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 89 0 0 0 0 0 0 0 0 0 0 12 0 % I
% Lys: 0 0 0 0 0 0 12 0 0 12 89 0 0 0 0 % K
% Leu: 0 6 0 0 18 83 0 12 0 0 0 0 0 0 12 % L
% Met: 0 6 0 48 65 18 0 0 0 0 0 0 0 0 42 % M
% Asn: 0 0 0 0 0 0 0 0 6 0 0 0 6 0 0 % N
% Pro: 12 0 0 0 0 0 0 6 0 0 0 100 0 0 0 % P
% Gln: 0 0 0 6 0 0 6 12 0 53 0 0 12 0 6 % Q
% Arg: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % R
% Ser: 89 89 0 30 0 0 12 53 18 0 0 0 0 0 12 % S
% Thr: 0 0 0 18 0 0 53 0 0 0 0 0 0 0 30 % T
% Val: 0 0 12 0 18 0 0 0 0 0 0 0 0 77 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _