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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC4
All Species:
62.12
Human Site:
Y111
Identified Species:
85.42
UniProt:
P43686
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43686
NP_006494.1
418
47366
Y111
G
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
Chimpanzee
Pan troglodytes
XP_001141067
422
47807
Y111
G
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
Rhesus Macaque
Macaca mulatta
XP_001090437
422
47818
Y111
G
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
Dog
Lupus familis
XP_867041
419
47479
Y111
G
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
Cat
Felis silvestris
Mouse
Mus musculus
P54775
418
47263
Y111
A
S
T
T
G
S
N
Y
Y
V
R
M
V
S
T
Rat
Rattus norvegicus
Q63570
418
47390
Y111
G
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518401
484
54060
Y213
G
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
Chicken
Gallus gallus
Q90732
440
49185
H131
S
T
S
V
G
S
E
H
Y
V
S
I
L
S
F
Frog
Xenopus laevis
NP_001083300
420
47373
Y113
G
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
Zebra Danio
Brachydanio rerio
NP_956044
418
47242
Y111
G
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
H130
S
T
S
V
G
S
E
H
Y
V
S
I
L
S
F
Honey Bee
Apis mellifera
XP_393513
415
47021
Y108
G
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
Nematode Worm
Caenorhab. elegans
P46502
414
46340
Y107
G
S
T
T
G
S
N
Y
Y
V
R
V
L
S
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002322593
412
46473
Y105
G
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
Maize
Zea mays
NP_001150600
420
46705
Y113
G
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEI4
408
45733
Y101
G
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
Baker's Yeast
Sacchar. cerevisiae
P33298
428
47951
Y118
S
S
T
T
G
M
S
Y
V
V
R
I
L
S
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99
99.5
N.A.
97.8
99.7
N.A.
73.9
45.2
95.9
96.6
N.A.
46
85.4
76.7
N.A.
Protein Similarity:
100
99
99
99.7
N.A.
98.3
99.7
N.A.
77.2
68.1
97.6
98.5
N.A.
70.1
92.5
85.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
80
100
N.A.
100
46.6
100
100
N.A.
46.6
100
86.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
100
66.6
100
100
N.A.
66.6
100
93.3
N.A.
Percent
Protein Identity:
77.7
77.1
N.A.
77
67.2
N.A.
Protein Similarity:
87.3
85.7
N.A.
85.8
81.7
N.A.
P-Site Identity:
100
100
N.A.
100
73.3
N.A.
P-Site Similarity:
100
100
N.A.
100
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
77
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
89
0
0
6
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
95
0
0
% L
% Met:
0
0
0
0
0
6
0
0
0
0
0
6
0
0
0
% M
% Asn:
0
0
0
0
0
0
83
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
89
0
0
0
0
% R
% Ser:
18
89
12
0
0
95
6
0
0
0
12
0
0
100
0
% S
% Thr:
0
12
89
89
0
0
0
0
0
0
0
0
0
0
83
% T
% Val:
0
0
0
12
0
0
0
0
6
100
0
6
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
89
95
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _