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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC4
All Species:
52.73
Human Site:
Y403
Identified Species:
72.5
UniProt:
P43686
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43686
NP_006494.1
418
47366
Y403
A
K
D
F
E
K
A
Y
K
T
V
I
K
K
D
Chimpanzee
Pan troglodytes
XP_001141067
422
47807
Y407
A
K
D
F
E
K
A
Y
K
T
V
I
K
K
D
Rhesus Macaque
Macaca mulatta
XP_001090437
422
47818
Y407
A
K
D
F
E
K
A
Y
K
T
V
I
K
K
D
Dog
Lupus familis
XP_867041
419
47479
Y404
A
K
D
F
E
K
A
Y
K
T
V
I
K
K
D
Cat
Felis silvestris
Mouse
Mus musculus
P54775
418
47263
Y403
A
K
D
F
E
K
A
Y
K
T
V
I
K
K
D
Rat
Rattus norvegicus
Q63570
418
47390
Y403
A
K
D
F
E
K
A
Y
K
T
V
I
K
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518401
484
54060
Y465
E
E
V
D
L
E
D
Y
V
A
R
P
D
K
I
Chicken
Gallus gallus
Q90732
440
49185
K423
N
E
D
F
K
K
S
K
E
N
F
L
Y
K
K
Frog
Xenopus laevis
NP_001083300
420
47373
Y405
A
K
D
F
E
K
A
Y
K
T
V
I
K
K
D
Zebra Danio
Brachydanio rerio
NP_956044
418
47242
Y403
A
K
D
F
E
K
A
Y
K
T
V
I
K
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
K422
N
E
D
F
K
K
S
K
E
S
V
L
Y
R
K
Honey Bee
Apis mellifera
XP_393513
415
47021
Y400
A
K
D
F
E
K
G
Y
K
N
N
I
K
K
D
Nematode Worm
Caenorhab. elegans
P46502
414
46340
Y399
T
K
D
L
E
K
A
Y
K
N
V
V
K
K
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002322593
412
46473
Y397
P
K
D
F
E
K
G
Y
R
T
N
V
K
K
P
Maize
Zea mays
NP_001150600
420
46705
Y405
P
K
D
F
E
K
G
Y
R
T
N
V
K
K
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEI4
408
45733
Y393
P
K
D
F
E
K
G
Y
R
A
N
V
K
K
P
Baker's Yeast
Sacchar. cerevisiae
P33298
428
47951
Y411
Q
S
D
L
E
E
A
Y
A
T
Q
V
K
T
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99
99.5
N.A.
97.8
99.7
N.A.
73.9
45.2
95.9
96.6
N.A.
46
85.4
76.7
N.A.
Protein Similarity:
100
99
99
99.7
N.A.
98.3
99.7
N.A.
77.2
68.1
97.6
98.5
N.A.
70.1
92.5
85.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
26.6
100
100
N.A.
26.6
80
73.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
60
100
100
N.A.
73.3
80
80
N.A.
Percent
Protein Identity:
77.7
77.1
N.A.
77
67.2
N.A.
Protein Similarity:
87.3
85.7
N.A.
85.8
81.7
N.A.
P-Site Identity:
60
60
N.A.
53.3
46.6
N.A.
P-Site Similarity:
73.3
73.3
N.A.
66.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
53
0
0
0
0
0
59
0
6
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
95
6
0
0
6
0
0
0
0
0
6
0
65
% D
% Glu:
6
18
0
0
83
12
0
0
12
0
0
0
0
0
0
% E
% Phe:
0
0
0
83
0
0
0
0
0
0
6
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
24
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
53
0
0
6
% I
% Lys:
0
77
0
0
12
89
0
12
59
0
0
0
83
89
12
% K
% Leu:
0
0
0
12
6
0
0
0
0
0
0
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
18
24
0
0
0
0
% N
% Pro:
18
0
0
0
0
0
0
0
0
0
0
6
0
0
18
% P
% Gln:
6
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
18
0
6
0
0
6
0
% R
% Ser:
0
6
0
0
0
0
12
0
0
6
0
0
0
0
0
% S
% Thr:
6
0
0
0
0
0
0
0
0
65
0
0
0
6
0
% T
% Val:
0
0
6
0
0
0
0
0
6
0
59
30
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
89
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _