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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC4
All Species:
48.79
Human Site:
Y41
Identified Species:
67.08
UniProt:
P43686
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43686
NP_006494.1
418
47366
Y41
P
E
D
L
E
D
L
Y
S
R
Y
K
K
L
Q
Chimpanzee
Pan troglodytes
XP_001141067
422
47807
Y41
P
E
D
L
E
D
L
Y
S
R
Y
K
K
L
Q
Rhesus Macaque
Macaca mulatta
XP_001090437
422
47818
Y41
P
E
D
L
E
D
L
Y
S
R
Y
K
K
L
Q
Dog
Lupus familis
XP_867041
419
47479
Y41
P
E
D
L
E
D
L
Y
S
R
Y
K
K
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
P54775
418
47263
Y41
P
E
D
L
E
D
L
Y
S
R
Y
K
K
L
Q
Rat
Rattus norvegicus
Q63570
418
47390
Y41
P
E
D
L
E
D
L
Y
S
R
Y
K
K
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518401
484
54060
A143
V
E
K
T
H
V
A
A
R
G
W
R
K
L
Q
Chicken
Gallus gallus
Q90732
440
49185
V52
A
A
S
K
P
P
L
V
T
P
H
T
Q
C
R
Frog
Xenopus laevis
NP_001083300
420
47373
Y43
P
E
D
L
E
D
L
Y
S
R
Y
K
K
L
Q
Zebra Danio
Brachydanio rerio
NP_956044
418
47242
Y41
P
E
D
L
E
D
L
Y
S
I
Y
K
K
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
V51
A
A
M
K
L
P
Q
V
T
P
H
T
R
C
R
Honey Bee
Apis mellifera
XP_393513
415
47021
Y38
E
L
D
V
E
D
L
Y
T
K
Y
K
K
L
Q
Nematode Worm
Caenorhab. elegans
P46502
414
46340
Y37
V
D
V
S
S
D
D
Y
I
K
L
T
T
L
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002322593
412
46473
Y35
P
I
E
D
D
D
L
Y
S
R
L
K
S
L
Q
Maize
Zea mays
NP_001150600
420
46705
Y43
V
E
E
E
D
D
L
Y
G
R
L
K
S
L
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEI4
408
45733
Y31
T
A
D
E
E
D
L
Y
G
R
L
K
S
L
E
Baker's Yeast
Sacchar. cerevisiae
P33298
428
47951
Y48
S
N
V
N
S
D
I
Y
F
K
L
K
K
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99
99.5
N.A.
97.8
99.7
N.A.
73.9
45.2
95.9
96.6
N.A.
46
85.4
76.7
N.A.
Protein Similarity:
100
99
99
99.7
N.A.
98.3
99.7
N.A.
77.2
68.1
97.6
98.5
N.A.
70.1
92.5
85.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
26.6
6.6
100
93.3
N.A.
0
66.6
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
33.3
100
93.3
N.A.
26.6
86.6
40
N.A.
Percent
Protein Identity:
77.7
77.1
N.A.
77
67.2
N.A.
Protein Similarity:
87.3
85.7
N.A.
85.8
81.7
N.A.
P-Site Identity:
60
53.3
N.A.
53.3
33.3
N.A.
P-Site Similarity:
73.3
66.6
N.A.
60
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
18
0
0
0
0
6
6
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
0
6
59
6
12
83
6
0
0
0
0
0
0
0
0
% D
% Glu:
6
59
12
12
59
0
0
0
0
0
0
0
0
0
18
% E
% Phe:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
6
0
0
0
0
0
% G
% His:
0
0
0
0
6
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
6
0
0
0
0
6
0
6
6
0
0
0
0
0
% I
% Lys:
0
0
6
12
0
0
0
0
0
18
0
77
65
0
0
% K
% Leu:
0
6
0
48
6
0
77
0
0
0
30
0
0
89
0
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
6
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
53
0
0
0
6
12
0
0
0
12
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
6
0
0
0
0
0
6
0
71
% Q
% Arg:
0
0
0
0
0
0
0
0
6
59
0
6
6
0
12
% R
% Ser:
6
0
6
6
12
0
0
0
53
0
0
0
18
0
0
% S
% Thr:
6
0
0
6
0
0
0
0
18
0
0
18
6
0
0
% T
% Val:
18
0
12
6
0
6
0
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
83
0
0
53
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _