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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GATA4 All Species: 9.7
Human Site: S381 Identified Species: 19.39
UniProt: P43694 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43694 NP_002043.2 442 44565 S381 Y G H S S S V S Q T F S V S A
Chimpanzee Pan troglodytes XP_528070 398 40497 Q338 G H S S S V S Q T F S V S A M
Rhesus Macaque Macaca mulatta XP_001087008 442 44546 S381 Y G H S S S V S Q T F S V S A
Dog Lupus familis XP_543086 400 41140 P339 P K P S L A S P S C P G S S I
Cat Felis silvestris
Mouse Mus musculus Q08369 440 44525 S379 S S H Y G H S S S M S Q T S V
Rat Rattus norvegicus P46152 440 44579 S379 S H Y G H S S S M S Q T F S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514983 248 26355 G188 F S V S T M T G H R A S V H P
Chicken Gallus gallus P43691 380 40658 Q320 G H P S P I S Q A F S V S A M
Frog Xenopus laevis Q91677 392 42335 P332 K I E P G L S P P Y D H S N S
Zebra Danio Brachydanio rerio Q91428 438 47572 S374 K S K K S H D S M E D F S K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P28515 416 44804 E356 S S I S S G I E L D Q S G V W
Sea Urchin Strong. purpuratus NP_001005725 567 60358 S506 L H N G P A N S A I N P L N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.3 98.1 42.7 N.A. 90 93.6 N.A. 38.6 63.3 60.4 36.2 N.A. N.A. N.A. 29.1 32.9
Protein Similarity: 100 89.3 99 53.3 N.A. 93.2 95.6 N.A. 43.4 71 69.4 48.1 N.A. N.A. N.A. 41.8 44.6
P-Site Identity: 100 13.3 100 13.3 N.A. 20 20 N.A. 20 6.6 0 13.3 N.A. N.A. N.A. 20 6.6
P-Site Similarity: 100 20 100 20 N.A. 20 40 N.A. 33.3 13.3 13.3 20 N.A. N.A. N.A. 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 17 0 0 17 0 9 0 0 17 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 9 0 0 9 17 0 0 0 0 % D
% Glu: 0 0 9 0 0 0 0 9 0 9 0 0 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 0 17 17 9 9 0 0 % F
% Gly: 17 17 0 17 17 9 0 9 0 0 0 9 9 0 0 % G
% His: 0 34 25 0 9 17 0 0 9 0 0 9 0 9 0 % H
% Ile: 0 9 9 0 0 9 9 0 0 9 0 0 0 0 9 % I
% Lys: 17 9 9 9 0 0 0 0 0 0 0 0 0 9 0 % K
% Leu: 9 0 0 0 9 9 0 0 9 0 0 0 9 0 9 % L
% Met: 0 0 0 0 0 9 0 0 17 9 0 0 0 0 17 % M
% Asn: 0 0 9 0 0 0 9 0 0 0 9 0 0 17 0 % N
% Pro: 9 0 17 9 17 0 0 17 9 0 9 9 0 0 9 % P
% Gln: 0 0 0 0 0 0 0 17 17 0 17 9 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % R
% Ser: 25 34 9 59 42 25 50 50 17 9 25 34 42 42 17 % S
% Thr: 0 0 0 0 9 0 9 0 9 17 0 9 9 0 9 % T
% Val: 0 0 9 0 0 9 17 0 0 0 0 17 25 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 17 0 9 9 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _