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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSFM
All Species:
19.09
Human Site:
S223
Identified Species:
42
UniProt:
P43897
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43897
NP_005717.3
325
35391
S223
Y
V
H
G
A
M
Q
S
P
S
L
H
K
L
V
Chimpanzee
Pan troglodytes
XP_509176
325
35364
S223
Y
V
H
G
A
M
Q
S
P
S
L
H
K
L
V
Rhesus Macaque
Macaca mulatta
XP_001116504
325
35308
S223
Y
V
H
G
A
M
Q
S
P
S
L
H
N
L
V
Dog
Lupus familis
XP_538255
432
47240
S330
Y
V
H
G
A
M
H
S
S
S
L
H
N
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZR8
324
35316
S222
Y
V
H
G
V
T
Q
S
P
S
L
Q
N
L
V
Rat
Rattus norvegicus
Q9QYU2
324
35160
S222
Y
V
H
G
E
M
Q
S
P
S
L
Q
N
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001091158
312
34400
A204
Y
M
H
G
I
L
M
A
D
L
P
S
L
T
N
Zebra Danio
Brachydanio rerio
NP_001073504
305
33456
G209
Y
I
H
G
T
V
A
G
Q
V
G
I
E
M
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609847
318
35394
G204
H
P
A
P
T
N
V
G
T
T
E
G
I
T
Q
Honey Bee
Apis mellifera
XP_391904
302
34031
L207
S
F
G
R
Y
G
A
L
L
A
L
K
S
D
K
Nematode Worm
Caenorhab. elegans
NP_506079
316
34069
N215
F
I
S
L
I
A
L
N
Q
S
S
P
G
S
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.3
64.1
N.A.
85.5
84.9
N.A.
N.A.
N.A.
62.7
47.6
N.A.
39
40.9
29.2
N.A.
Protein Similarity:
100
99.6
97.5
68.9
N.A.
88.3
87.6
N.A.
N.A.
N.A.
76.6
66.4
N.A.
52.9
57.8
50.4
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
73.3
80
N.A.
N.A.
N.A.
20
20
N.A.
0
6.6
6.6
N.A.
P-Site Similarity:
100
100
93.3
73.3
N.A.
73.3
80
N.A.
N.A.
N.A.
40
46.6
N.A.
13.3
13.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
37
10
19
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
10
0
10
0
10
% E
% Phe:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
73
0
10
0
19
0
0
10
10
10
0
10
% G
% His:
10
0
73
0
0
0
10
0
0
0
0
37
0
0
0
% H
% Ile:
0
19
0
0
19
0
0
0
0
0
0
10
10
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
19
0
10
% K
% Leu:
0
0
0
10
0
10
10
10
10
10
64
0
10
55
0
% L
% Met:
0
10
0
0
0
46
10
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
0
0
0
37
0
10
% N
% Pro:
0
10
0
10
0
0
0
0
46
0
10
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
46
0
19
0
0
19
0
0
10
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
10
0
0
0
0
55
10
64
10
10
10
10
0
% S
% Thr:
0
0
0
0
19
10
0
0
10
10
0
0
0
19
0
% T
% Val:
0
55
0
0
10
10
10
0
0
10
0
0
0
0
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
73
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _