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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSFM All Species: 15.45
Human Site: S285 Identified Species: 34
UniProt: P43897 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43897 NP_005717.3 325 35391 S285 E A E T K M L S Q P Y L L D P
Chimpanzee Pan troglodytes XP_509176 325 35364 S285 E A E T K M L S Q P Y L L D P
Rhesus Macaque Macaca mulatta XP_001116504 325 35308 S285 E A E T K M L S Q P Y L L D P
Dog Lupus familis XP_538255 432 47240 S392 E A E T K M L S Q P Y L L D P
Cat Felis silvestris
Mouse Mus musculus Q9CZR8 324 35316 P284 E T E T R M L P Q P Y L L D P
Rat Rattus norvegicus Q9QYU2 324 35160 P284 E T E T R M L P Q P Y L L D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001091158 312 34400 A270 E T E T K M L A Q P F L L E P
Zebra Danio Brachydanio rerio NP_001073504 305 33456 P268 D S E T R L L P Q T F L P D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609847 318 35394 H268 D D E T C L I H Q E Y L L D A
Honey Bee Apis mellifera XP_391904 302 34031 I266 L F N P A L S I Q Q L L Q N E
Nematode Worm Caenorhab. elegans NP_506079 316 34069 T272 N A D P V V V T N I D E S E T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 95.3 64.1 N.A. 85.5 84.9 N.A. N.A. N.A. 62.7 47.6 N.A. 39 40.9 29.2 N.A.
Protein Similarity: 100 99.6 97.5 68.9 N.A. 88.3 87.6 N.A. N.A. N.A. 76.6 66.4 N.A. 52.9 57.8 50.4 N.A.
P-Site Identity: 100 100 100 100 N.A. 80 80 N.A. N.A. N.A. 73.3 46.6 N.A. 46.6 13.3 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. N.A. N.A. 93.3 80 N.A. 66.6 26.6 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 46 0 0 10 0 0 10 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 10 10 0 0 0 0 0 0 0 10 0 0 73 0 % D
% Glu: 64 0 82 0 0 0 0 0 0 10 0 10 0 19 10 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 19 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 10 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 46 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 28 73 0 0 0 10 91 73 0 0 % L
% Met: 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 10 0 0 0 0 0 10 0 0 0 0 10 0 % N
% Pro: 0 0 0 19 0 0 0 28 0 64 0 0 10 0 73 % P
% Gln: 0 0 0 0 0 0 0 0 91 10 0 0 10 0 0 % Q
% Arg: 0 0 0 0 28 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 0 0 10 37 0 0 0 0 10 0 0 % S
% Thr: 0 28 0 82 0 0 0 10 0 10 0 0 0 0 10 % T
% Val: 0 0 0 0 10 10 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 64 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _