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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNNT3 All Species: 16.97
Human Site: T217 Identified Species: 37.33
UniProt: P45378 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P45378 NP_001036245.1 269 31825 T217 K A K E L W E T L H Q L E I D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001091834 250 29735 T198 K A K E L W E T L H Q L E T D
Dog Lupus familis XP_863139 314 36615 T262 K A K E L W D T L Y Q L E T D
Cat Felis silvestris
Mouse Mus musculus Q9QZ47 272 32222 T220 K A K E L W D T L Y Q L E T D
Rat Rattus norvegicus P09739 259 30732 T207 K A K E L W D T L Y Q L E T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516242 219 26174 W170 K A K E L S D W I H Q L E S E
Chicken Gallus gallus P12620 263 31123 W213 K A K E L W D W L Y Q L Q T E
Frog Xenopus laevis NP_001080403 276 32844 W225 K A K E M W D W L Y Q L E S E
Zebra Danio Brachydanio rerio NP_857636 232 27812 W186 K A K E L W D W L Y S L E A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P19351 397 47429 L207 K A Q E L W E L I V K L E T E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27371 405 47023 R242 R I R G L H A R I V K L E A E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 92.1 73.5 N.A. 89.3 91.8 N.A. 57.2 82.1 73.9 62.4 N.A. 20.3 N.A. 26.6 N.A.
Protein Similarity: 100 N.A. 92.1 77.7 N.A. 92.2 93.3 N.A. 69.1 89.2 86.5 74.7 N.A. 38.5 N.A. 38.7 N.A.
P-Site Identity: 100 N.A. 93.3 80 N.A. 80 80 N.A. 60 60 60 60 N.A. 53.3 N.A. 20 N.A.
P-Site Similarity: 100 N.A. 93.3 93.3 N.A. 93.3 93.3 N.A. 80 86.6 86.6 80 N.A. 80 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 91 0 0 0 0 10 0 0 0 0 0 0 19 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 64 0 0 0 0 0 0 0 46 % D
% Glu: 0 0 0 91 0 0 28 0 0 0 0 0 91 0 55 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 28 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 28 0 0 0 0 10 0 % I
% Lys: 91 0 82 0 0 0 0 0 0 0 19 0 0 0 0 % K
% Leu: 0 0 0 0 91 0 0 10 73 0 0 100 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 73 0 10 0 0 % Q
% Arg: 10 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 0 0 0 0 10 0 0 19 0 % S
% Thr: 0 0 0 0 0 0 0 46 0 0 0 0 0 55 0 % T
% Val: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 82 0 37 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 55 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _