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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNNT3 All Species: 4.55
Human Site: T258 Identified Species: 10
UniProt: P45378 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P45378 NP_001036245.1 269 31825 T258 K H S K K A G T P A K G K V G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001091834 250 29735 T239 K H S K K A G T P A K G K V G
Dog Lupus familis XP_863139 314 36615 A303 K H S K K A G A P A K G K V G
Cat Felis silvestris
Mouse Mus musculus Q9QZ47 272 32222 A261 K H S K K A G A T A K G K V G
Rat Rattus norvegicus P09739 259 30732 A248 K H S K K A G A T A K G K V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516242 219 26174 K211 K F K K G A A K G R V G G R W
Chicken Gallus gallus P12620 263 31123 A254 K H S K K A G A K G K V G G R
Frog Xenopus laevis NP_001080403 276 32844 G266 K F S K K A A G G K G K V G G
Zebra Danio Brachydanio rerio NP_857636 232 27812 K224 E L S K Y S K K G A A A R R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P19351 397 47429 G248 R H K A L K K G L D P E A L T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27371 405 47023 G283 R N K A L K K G L D P E E A A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 92.1 73.5 N.A. 89.3 91.8 N.A. 57.2 82.1 73.9 62.4 N.A. 20.3 N.A. 26.6 N.A.
Protein Similarity: 100 N.A. 92.1 77.7 N.A. 92.2 93.3 N.A. 69.1 89.2 86.5 74.7 N.A. 38.5 N.A. 38.7 N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 86.6 86.6 N.A. 26.6 53.3 40 20 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 N.A. 100 93.3 N.A. 86.6 86.6 N.A. 26.6 53.3 40 40 N.A. 20 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 0 73 19 37 0 55 10 10 10 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 0 0 19 10 0 0 % E
% Phe: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 55 28 28 10 10 55 19 19 55 % G
% His: 0 64 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 73 0 28 82 64 19 28 19 10 10 55 10 46 0 0 % K
% Leu: 0 10 0 0 19 0 0 0 19 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 28 0 19 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 19 0 0 0 0 0 0 0 0 10 0 0 10 19 19 % R
% Ser: 0 0 73 0 0 10 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 19 19 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 10 10 46 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _