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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASPA
All Species:
37.27
Human Site:
Y88
Identified Species:
91.11
UniProt:
P45381
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45381
NP_000040.1
313
35735
Y88
K
M
S
E
D
L
P
Y
E
V
R
R
A
Q
E
Chimpanzee
Pan troglodytes
XP_511268
261
29775
Y88
K
M
S
E
D
L
P
Y
E
V
R
R
A
Q
E
Rhesus Macaque
Macaca mulatta
XP_001089160
313
35712
Y88
K
M
S
E
D
L
P
Y
E
V
R
R
A
Q
E
Dog
Lupus familis
XP_854515
313
35736
Y88
K
V
S
K
D
L
P
Y
E
V
R
R
A
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3P0
312
35326
Y87
E
M
S
E
D
L
P
Y
E
V
R
R
A
Q
E
Rat
Rattus norvegicus
Q9R1T5
312
35295
Y87
E
M
S
E
D
L
P
Y
E
V
R
R
A
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508678
315
35756
Y89
K
E
T
E
N
L
P
Y
E
I
R
R
A
Q
E
Chicken
Gallus gallus
XP_415853
345
39116
Y115
T
V
V
E
D
I
P
Y
E
V
R
R
A
Q
E
Frog
Xenopus laevis
A0JMS7
305
34292
Y82
S
A
S
E
S
D
S
Y
E
V
K
R
A
R
E
Zebra Danio
Brachydanio rerio
A8KB34
315
35516
Y90
S
E
L
E
A
L
P
Y
E
V
Q
R
A
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.4
96.8
90.4
N.A.
86.2
86.9
N.A.
79
65.2
43.7
60.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
82.7
98
96.1
N.A.
95.2
95.5
N.A.
90.1
78.5
64.8
76.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
73.3
73.3
53.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
86.6
66.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
0
0
0
0
0
100
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
70
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
20
20
0
90
0
0
0
0
100
0
0
0
0
0
100
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% I
% Lys:
50
0
0
10
0
0
0
0
0
0
10
0
0
10
0
% K
% Leu:
0
0
10
0
0
80
0
0
0
0
0
0
0
0
0
% L
% Met:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
90
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
80
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
80
100
0
10
0
% R
% Ser:
20
0
70
0
10
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
20
10
0
0
0
0
0
0
90
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _