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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIC
All Species:
16.36
Human Site:
T189
Identified Species:
24
UniProt:
P45877
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45877
NP_000934.1
212
22763
T189
D
G
H
D
R
P
L
T
N
C
S
I
I
N
S
Chimpanzee
Pan troglodytes
XP_001174161
216
23752
K195
D
S
R
D
K
P
L
K
D
V
I
I
A
D
C
Rhesus Macaque
Macaca mulatta
XP_001093271
212
22597
T189
D
G
H
D
R
P
L
T
N
C
S
I
V
N
S
Dog
Lupus familis
XP_538601
274
30146
T251
D
G
H
D
R
P
L
T
D
C
S
I
V
N
S
Cat
Felis silvestris
Mouse
Mus musculus
P30412
212
22776
T189
D
G
H
D
R
P
L
T
D
C
T
I
V
N
S
Rat
Rattus norvegicus
P24368
216
23784
K195
D
S
R
D
K
P
L
K
D
V
I
I
V
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508975
216
23586
K195
D
G
R
D
K
P
L
K
D
V
T
I
T
D
C
Chicken
Gallus gallus
P24367
207
22394
K186
D
S
R
D
K
P
L
K
D
V
T
I
A
D
C
Frog
Xenopus laevis
NP_001080505
216
23841
K195
D
G
R
D
K
P
L
K
D
V
V
I
A
D
C
Zebra Danio
Brachydanio rerio
XP_002667876
208
22853
T185
N
E
R
N
L
P
Y
T
E
C
V
I
V
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25007
227
24648
V201
E
V
V
E
G
L
D
V
V
K
K
I
E
S
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52014
201
21845
E177
G
A
G
D
R
P
I
E
D
V
V
I
A
N
A
Sea Urchin
Strong. purpuratus
XP_797957
196
21187
K168
G
D
N
D
K
P
V
K
D
C
V
I
A
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P34791
260
28190
F204
N
T
N
G
S
Q
F
F
I
C
T
V
K
T
S
Baker's Yeast
Sacchar. cerevisiae
P23285
205
22750
A183
I
Q
H
V
S
R
D
A
N
D
K
P
L
E
A
Red Bread Mold
Neurospora crassa
Q7S7Z6
285
30725
E186
G
P
R
D
A
P
A
E
P
I
K
I
A
K
S
Conservation
Percent
Protein Identity:
100
63.4
96.6
66
N.A.
90.5
62.5
N.A.
64.8
64.1
63.8
67.9
N.A.
47.5
N.A.
61.7
61.7
Protein Similarity:
100
73.6
98.5
71.1
N.A.
94.3
73.1
N.A.
77.7
75.4
74.5
76.4
N.A.
56.3
N.A.
70.7
72.1
P-Site Identity:
100
33.3
93.3
86.6
N.A.
80
33.3
N.A.
40
33.3
40
40
N.A.
6.6
N.A.
33.3
33.3
P-Site Similarity:
100
53.3
100
100
N.A.
100
60
N.A.
66.6
60
60
60
N.A.
26.6
N.A.
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.3
50.4
44.5
Protein Similarity:
N.A.
N.A.
N.A.
58.4
64.6
53.6
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
0
7
7
0
0
0
0
38
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
44
0
0
0
0
32
% C
% Asp:
57
7
0
75
0
0
13
0
57
7
0
0
0
38
0
% D
% Glu:
7
7
0
7
0
0
0
13
7
0
0
0
7
7
0
% E
% Phe:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% F
% Gly:
19
38
7
7
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
32
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
7
0
7
7
13
88
7
0
0
% I
% Lys:
0
0
0
0
38
0
0
38
0
7
19
0
7
7
0
% K
% Leu:
0
0
0
0
7
7
57
0
0
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
13
7
0
0
0
0
19
0
0
0
0
38
0
% N
% Pro:
0
7
0
0
0
82
0
0
7
0
0
7
0
0
0
% P
% Gln:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
44
0
32
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
19
0
0
13
0
0
0
0
0
19
0
0
7
50
% S
% Thr:
0
7
0
0
0
0
0
32
0
0
25
0
7
7
0
% T
% Val:
0
7
7
7
0
0
7
7
7
38
25
7
32
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _