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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIC
All Species:
47.58
Human Site:
Y127
Identified Species:
69.78
UniProt:
P45877
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45877
NP_000934.1
212
22763
Y127
E
N
F
K
L
K
H
Y
G
I
G
W
V
S
M
Chimpanzee
Pan troglodytes
XP_001174161
216
23752
Y133
E
N
F
K
L
K
H
Y
G
P
G
W
V
S
M
Rhesus Macaque
Macaca mulatta
XP_001093271
212
22597
Y127
E
N
F
K
L
K
H
Y
G
I
G
W
V
S
M
Dog
Lupus familis
XP_538601
274
30146
Y189
E
N
F
K
L
K
H
Y
G
I
G
W
V
S
M
Cat
Felis silvestris
Mouse
Mus musculus
P30412
212
22776
Y127
E
N
F
K
L
K
H
Y
G
I
G
W
V
S
M
Rat
Rattus norvegicus
P24368
216
23784
Y133
E
N
F
K
L
K
H
Y
G
P
G
W
V
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508975
216
23586
Y133
E
N
F
K
L
K
H
Y
G
P
G
W
V
S
M
Chicken
Gallus gallus
P24367
207
22394
Y124
E
N
F
K
L
K
H
Y
G
P
G
W
V
S
M
Frog
Xenopus laevis
NP_001080505
216
23841
Y133
E
N
F
K
L
K
H
Y
G
P
F
W
L
S
M
Zebra Danio
Brachydanio rerio
XP_002667876
208
22853
L123
E
N
F
R
L
R
H
L
G
A
G
W
V
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25007
227
24648
V119
K
G
S
I
F
H
R
V
I
P
N
F
M
C
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52014
201
21845
Y115
E
N
F
K
L
Q
H
Y
G
P
G
W
L
S
M
Sea Urchin
Strong. purpuratus
XP_797957
196
21187
Y106
E
N
F
K
L
S
H
Y
G
A
G
W
L
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P34791
260
28190
T132
E
N
F
R
A
L
C
T
G
E
K
K
Y
G
Y
Baker's Yeast
Sacchar. cerevisiae
P23285
205
22750
F121
D
T
F
P
D
E
N
F
T
L
K
H
D
R
K
Red Bread Mold
Neurospora crassa
Q7S7Z6
285
30725
S124
E
N
F
K
L
K
H
S
K
K
G
L
L
S
M
Conservation
Percent
Protein Identity:
100
63.4
96.6
66
N.A.
90.5
62.5
N.A.
64.8
64.1
63.8
67.9
N.A.
47.5
N.A.
61.7
61.7
Protein Similarity:
100
73.6
98.5
71.1
N.A.
94.3
73.1
N.A.
77.7
75.4
74.5
76.4
N.A.
56.3
N.A.
70.7
72.1
P-Site Identity:
100
93.3
100
100
N.A.
100
93.3
N.A.
93.3
93.3
80
73.3
N.A.
0
N.A.
80
80
P-Site Similarity:
100
93.3
100
100
N.A.
100
93.3
N.A.
93.3
93.3
86.6
86.6
N.A.
20
N.A.
93.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.3
50.4
44.5
Protein Similarity:
N.A.
N.A.
N.A.
58.4
64.6
53.6
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
0
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% C
% Asp:
7
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% D
% Glu:
88
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% E
% Phe:
0
0
94
0
7
0
0
7
0
0
7
7
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
82
0
75
0
0
7
0
% G
% His:
0
0
0
0
0
7
82
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
7
25
0
0
0
0
0
% I
% Lys:
7
0
0
75
0
63
0
0
7
7
13
7
0
0
7
% K
% Leu:
0
0
0
0
82
7
0
7
0
7
0
7
25
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
82
% M
% Asn:
0
88
0
0
0
0
7
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
44
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
0
13
0
7
7
0
0
0
0
0
0
7
0
% R
% Ser:
0
0
7
0
0
7
0
7
0
0
0
0
0
82
0
% S
% Thr:
0
7
0
0
0
0
0
7
7
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
7
0
0
0
0
57
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
69
0
0
0
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _