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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VDAC2
All Species:
47.27
Human Site:
S251
Identified Species:
74.29
UniProt:
P45880
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45880
NP_003366.2
294
31567
S251
I
S
A
K
V
N
N
S
S
L
I
G
V
G
Y
Chimpanzee
Pan troglodytes
XP_001139116
294
31631
S251
I
S
A
K
V
N
N
S
S
L
I
G
V
G
Y
Rhesus Macaque
Macaca mulatta
XP_001096479
283
30408
S240
I
S
A
K
V
N
N
S
S
L
I
G
V
G
Y
Dog
Lupus familis
XP_851742
294
31560
S251
I
S
A
K
V
N
N
S
S
L
I
G
V
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q60930
295
31714
S252
I
S
A
K
V
N
N
S
S
L
I
G
V
G
Y
Rat
Rattus norvegicus
P81155
295
31727
S252
I
S
A
K
V
N
N
S
S
L
I
G
V
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505832
283
30297
S240
I
S
A
K
V
N
N
S
S
L
I
G
V
G
Y
Chicken
Gallus gallus
NP_990072
283
30179
S240
I
S
A
K
V
N
N
S
S
L
V
G
V
G
Y
Frog
Xenopus laevis
P81004
282
30052
S239
I
S
A
K
V
N
N
S
S
L
V
G
V
G
Y
Zebra Danio
Brachydanio rerio
NP_955879
283
30265
T240
I
S
A
K
V
N
N
T
S
L
V
G
V
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94920
282
30532
A239
V
R
A
K
V
N
N
A
S
Q
V
G
L
G
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21752
283
29942
S240
V
R
A
K
V
N
S
S
S
Q
V
A
V
A
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SMX3
274
29192
A232
V
K
A
R
V
N
N
A
G
V
A
N
A
L
I
Baker's Yeast
Sacchar. cerevisiae
P04840
283
30410
S240
V
K
A
K
V
S
D
S
G
I
V
T
L
A
Y
Red Bread Mold
Neurospora crassa
P07144
283
29981
R240
V
K
G
K
I
N
D
R
G
V
A
A
I
A
Y
Conservation
Percent
Protein Identity:
100
99.6
95.9
98.6
N.A.
94.9
94.5
N.A.
92.8
86.7
82.6
80.2
N.A.
59.8
N.A.
39.7
N.A.
Protein Similarity:
100
99.6
96.2
100
N.A.
96.6
96.6
N.A.
95.2
93.5
91.1
90.4
N.A.
74.4
N.A.
59.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
86.6
N.A.
60
N.A.
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
86.6
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
23.8
30.2
Protein Similarity:
N.A.
N.A.
N.A.
42.1
42.1
48.3
P-Site Identity:
N.A.
N.A.
N.A.
26.6
33.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
73.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
94
0
0
0
0
14
0
0
14
14
7
20
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
20
0
0
74
0
74
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
67
0
0
0
7
0
0
0
0
7
47
0
7
0
7
% I
% Lys:
0
20
0
94
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
67
0
0
14
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
94
80
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% Q
% Arg:
0
14
0
7
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
67
0
0
0
7
7
74
80
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% T
% Val:
34
0
0
0
94
0
0
0
0
14
40
0
74
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
87
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _