KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VDAC2
All Species:
49.09
Human Site:
Y258
Identified Species:
77.14
UniProt:
P45880
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45880
NP_003366.2
294
31567
Y258
S
S
L
I
G
V
G
Y
T
Q
T
L
R
P
G
Chimpanzee
Pan troglodytes
XP_001139116
294
31631
Y258
S
S
L
I
G
V
G
Y
T
Q
T
L
R
P
G
Rhesus Macaque
Macaca mulatta
XP_001096479
283
30408
Y247
S
S
L
I
G
V
G
Y
T
Q
T
L
R
P
G
Dog
Lupus familis
XP_851742
294
31560
Y258
S
S
L
I
G
V
G
Y
T
Q
T
L
R
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q60930
295
31714
Y259
S
S
L
I
G
V
G
Y
T
Q
T
L
R
P
G
Rat
Rattus norvegicus
P81155
295
31727
Y259
S
S
L
I
G
V
G
Y
T
Q
T
L
R
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505832
283
30297
Y247
S
S
L
I
G
V
G
Y
T
Q
T
L
R
P
G
Chicken
Gallus gallus
NP_990072
283
30179
Y247
S
S
L
V
G
V
G
Y
T
Q
T
L
R
P
G
Frog
Xenopus laevis
P81004
282
30052
Y246
S
S
L
V
G
V
G
Y
T
Q
T
L
R
P
G
Zebra Danio
Brachydanio rerio
NP_955879
283
30265
Y247
T
S
L
V
G
V
G
Y
T
Q
S
L
R
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94920
282
30532
Y246
A
S
Q
V
G
L
G
Y
Q
Q
K
L
R
D
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21752
283
29942
A247
S
S
Q
V
A
V
A
A
T
H
S
L
S
P
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SMX3
274
29192
I239
A
G
V
A
N
A
L
I
Q
H
E
W
R
P
K
Baker's Yeast
Sacchar. cerevisiae
P04840
283
30410
Y247
S
G
I
V
T
L
A
Y
K
Q
L
L
R
P
G
Red Bread Mold
Neurospora crassa
P07144
283
29981
Y247
R
G
V
A
A
I
A
Y
N
V
L
L
R
E
G
Conservation
Percent
Protein Identity:
100
99.6
95.9
98.6
N.A.
94.9
94.5
N.A.
92.8
86.7
82.6
80.2
N.A.
59.8
N.A.
39.7
N.A.
Protein Similarity:
100
99.6
96.2
100
N.A.
96.6
96.6
N.A.
95.2
93.5
91.1
90.4
N.A.
74.4
N.A.
59.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
80
N.A.
53.3
N.A.
40
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
73.3
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
23.8
30.2
Protein Similarity:
N.A.
N.A.
N.A.
42.1
42.1
48.3
P-Site Identity:
N.A.
N.A.
N.A.
13.3
46.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
66.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
14
14
7
20
7
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
20
0
0
74
0
74
0
0
0
0
0
0
0
87
% G
% His:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% H
% Ile:
0
0
7
47
0
7
0
7
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
7
% K
% Leu:
0
0
67
0
0
14
7
0
0
0
14
94
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
87
0
% P
% Gln:
0
0
14
0
0
0
0
0
14
80
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
0
0
0
0
0
94
0
0
% R
% Ser:
74
80
0
0
0
0
0
0
0
0
14
0
7
0
0
% S
% Thr:
7
0
0
0
7
0
0
0
74
0
60
0
0
0
0
% T
% Val:
0
0
14
40
0
74
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
87
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _