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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VDAC2
All Species:
37.58
Human Site:
Y73
Identified Species:
59.05
UniProt:
P45880
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45880
NP_003366.2
294
31567
Y73
T
G
T
L
E
T
K
Y
K
W
C
E
Y
G
L
Chimpanzee
Pan troglodytes
XP_001139116
294
31631
Y73
T
G
T
L
E
T
K
Y
K
W
C
E
Y
G
L
Rhesus Macaque
Macaca mulatta
XP_001096479
283
30408
Y62
T
G
T
L
E
T
K
Y
K
W
C
E
Y
G
L
Dog
Lupus familis
XP_851742
294
31560
Y73
T
G
T
L
E
T
K
Y
K
W
C
E
Y
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q60930
295
31714
Y74
S
G
T
L
E
T
K
Y
K
W
C
E
Y
G
L
Rat
Rattus norvegicus
P81155
295
31727
Y74
S
G
T
L
E
T
K
Y
K
W
C
E
Y
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505832
283
30297
Y62
N
G
T
L
E
T
K
Y
K
W
C
E
Y
G
L
Chicken
Gallus gallus
NP_990072
283
30179
Y62
N
G
S
L
E
T
K
Y
K
W
A
E
Y
G
L
Frog
Xenopus laevis
P81004
282
30052
G67
K
Y
K
W
G
E
Y
G
L
T
F
T
E
K
W
Zebra Danio
Brachydanio rerio
NP_955879
283
30265
Y62
V
G
S
L
E
T
K
Y
K
R
S
E
Y
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94920
282
30532
D65
E
T
K
Y
K
V
K
D
Y
G
L
T
L
T
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21752
283
29942
Y63
G
G
N
L
D
V
K
Y
K
I
P
Q
Y
G
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SMX3
274
29192
N62
D
V
A
T
Q
V
K
N
N
N
F
T
A
D
V
Baker's Yeast
Sacchar. cerevisiae
P04840
283
30410
L62
S
T
N
V
E
A
K
L
N
D
K
Q
T
G
L
Red Bread Mold
Neurospora crassa
P07144
283
29981
P65
E
G
K
F
T
D
K
P
N
G
L
T
V
T
Q
Conservation
Percent
Protein Identity:
100
99.6
95.9
98.6
N.A.
94.9
94.5
N.A.
92.8
86.7
82.6
80.2
N.A.
59.8
N.A.
39.7
N.A.
Protein Similarity:
100
99.6
96.2
100
N.A.
96.6
96.6
N.A.
95.2
93.5
91.1
90.4
N.A.
74.4
N.A.
59.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
80
0
73.3
N.A.
6.6
N.A.
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
86.6
0
80
N.A.
13.3
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
23.8
30.2
Protein Similarity:
N.A.
N.A.
N.A.
42.1
42.1
48.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
0
0
0
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% C
% Asp:
7
0
0
0
7
7
0
7
0
7
0
0
0
7
0
% D
% Glu:
14
0
0
0
67
7
0
0
0
0
0
60
7
0
7
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
14
0
0
0
0
% F
% Gly:
7
74
0
0
7
0
0
7
0
14
0
0
0
74
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% I
% Lys:
7
0
20
0
7
0
94
0
67
0
7
0
0
7
0
% K
% Leu:
0
0
0
67
0
0
0
7
7
0
14
0
7
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
0
14
0
0
0
0
7
20
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
14
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
20
0
14
0
0
0
0
0
0
0
7
0
0
0
0
% S
% Thr:
27
14
47
7
7
60
0
0
0
7
0
27
7
14
0
% T
% Val:
7
7
0
7
0
20
0
0
0
0
0
0
7
0
7
% V
% Trp:
0
0
0
7
0
0
0
0
0
54
0
0
0
0
7
% W
% Tyr:
0
7
0
7
0
0
7
67
7
0
0
0
67
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _