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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACADSB All Species: 23.94
Human Site: Y199 Identified Species: 52.67
UniProt: P45954 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P45954 NP_001600.1 432 47485 Y199 A D K E G D Y Y V L N G S K M
Chimpanzee Pan troglodytes A5A6I0 421 46589 I192 I N G Q K M W I T N G G K A N
Rhesus Macaque Macaca mulatta XP_001104844 432 47507 Y199 A D K E G D Y Y V L N G S K M
Dog Lupus familis XP_535048 521 56389 Y288 A D K K G N Y Y V I N G S K M
Cat Felis silvestris
Mouse Mus musculus Q9DBL1 432 47856 Y199 A D K S G N Y Y V L N G S K M
Rat Rattus norvegicus P70584 432 47805 Y199 A D K S G N Y Y V I N G S K M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026411 433 47726 Y200 A E K K G D Y Y I I N G S K M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSA3 419 45853 G192 K M W I T N G G V A N W Y F V
Honey Bee Apis mellifera XP_393211 422 46603 S191 D G S D Y V I S G T K M W I S
Nematode Worm Caenorhab. elegans Q22347 417 44800 F192 G G H A K W F F V L A R S D P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SWG0 409 44755 Y197 S A E T L V V Y A K T D T K A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.6 95.5 68.5 N.A. 82.6 83.5 N.A. N.A. 70.6 N.A. N.A. N.A. 34.9 55.5 35.1 N.A.
Protein Similarity: 100 56.7 98.8 76.3 N.A. 90.2 91.4 N.A. N.A. 83.8 N.A. N.A. N.A. 57.1 74 53.2 N.A.
P-Site Identity: 100 6.6 100 80 N.A. 86.6 80 N.A. N.A. 73.3 N.A. N.A. N.A. 13.3 0 20 N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 93.3 93.3 N.A. N.A. 100 N.A. N.A. N.A. 26.6 6.6 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 35.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 53.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 55 10 0 10 0 0 0 0 10 10 10 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 46 0 10 0 28 0 0 0 0 0 10 0 10 0 % D
% Glu: 0 10 10 19 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 10 0 0 0 0 0 10 0 % F
% Gly: 10 19 10 0 55 0 10 10 10 0 10 64 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 10 0 0 10 10 10 28 0 0 0 10 0 % I
% Lys: 10 0 55 19 19 0 0 0 0 10 10 0 10 64 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 37 0 0 0 0 0 % L
% Met: 0 10 0 0 0 10 0 0 0 0 0 10 0 0 55 % M
% Asn: 0 10 0 0 0 37 0 0 0 10 64 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 10 0 10 19 0 0 0 10 0 0 0 0 64 0 10 % S
% Thr: 0 0 0 10 10 0 0 0 10 10 10 0 10 0 0 % T
% Val: 0 0 0 0 0 19 10 0 64 0 0 0 0 0 10 % V
% Trp: 0 0 10 0 0 10 10 0 0 0 0 10 10 0 0 % W
% Tyr: 0 0 0 0 10 0 55 64 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _