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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CBX5 All Species: 13.33
Human Site: S92 Identified Species: 36.67
UniProt: P45973 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P45973 NP_001120793.1 191 22225 S92 S E S N K R K S N F S N S A D
Chimpanzee Pan troglodytes XP_001161192 173 19690 E88 R K S L S D S E S D D S K S K
Rhesus Macaque Macaca mulatta XP_001091785 283 31521 S185 S E S N K R K S N F S N S A D
Dog Lupus familis XP_534787 190 22105 S92 S E S N K R K S N F S N N A D
Cat Felis silvestris
Mouse Mus musculus Q61686 191 22167 S92 S E G N K R K S S F S N S A D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508853 184 20945 R92 E K T D G A K R K S L S D S E
Chicken Gallus gallus
Frog Xenopus laevis NP_001080863 199 22766 D108 T K R K A G S D D I K A K R R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P05205 206 23167 E96 S S S A K A K E T Q G R A S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q946J8 445 48626 K180 A G P H S Q M K K K Q R L T S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.2 67.1 98.9 N.A. 97.9 N.A. N.A. 64.4 N.A. 77.8 N.A. N.A. 46.1 N.A. N.A. N.A.
Protein Similarity: 100 73.3 67.1 99.4 N.A. 99.4 N.A. N.A. 75.9 N.A. 86.9 N.A. N.A. 62.1 N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 93.3 N.A. 86.6 N.A. N.A. 6.6 N.A. 0 N.A. N.A. 26.6 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 93.3 N.A. N.A. 46.6 N.A. 20 N.A. N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 28.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 12 12 23 0 0 0 0 0 12 12 45 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 12 0 12 0 12 12 12 12 0 12 0 45 % D
% Glu: 12 45 0 0 0 0 0 23 0 0 0 0 0 0 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 45 0 0 0 0 0 % F
% Gly: 0 12 12 0 12 12 0 0 0 0 12 0 0 0 0 % G
% His: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % I
% Lys: 0 34 0 12 56 0 67 12 23 12 12 0 23 0 12 % K
% Leu: 0 0 0 12 0 0 0 0 0 0 12 0 12 0 0 % L
% Met: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 45 0 0 0 0 34 0 0 45 12 0 0 % N
% Pro: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 12 0 0 0 12 12 0 0 0 0 % Q
% Arg: 12 0 12 0 0 45 0 12 0 0 0 23 0 12 12 % R
% Ser: 56 12 56 0 23 0 23 45 23 12 45 23 34 34 23 % S
% Thr: 12 0 12 0 0 0 0 0 12 0 0 0 0 12 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _