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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CBX5
All Species:
18.18
Human Site:
Y177
Identified Species:
50
UniProt:
P45973
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45973
NP_001120793.1
191
22225
Y177
E
R
L
T
W
H
A
Y
P
E
D
A
E
N
K
Chimpanzee
Pan troglodytes
XP_001161192
173
19690
E160
I
V
I
A
F
Y
E
E
R
L
T
W
H
S
C
Rhesus Macaque
Macaca mulatta
XP_001091785
283
31521
Y269
E
R
L
T
W
H
A
Y
P
E
D
A
E
N
K
Dog
Lupus familis
XP_534787
190
22105
Y176
E
R
L
T
W
H
A
Y
P
E
D
A
E
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61686
191
22167
Y177
E
R
L
T
W
H
A
Y
P
E
D
A
E
N
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508853
184
20945
E171
I
V
I
A
F
Y
E
E
R
L
T
W
H
S
C
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080863
199
22766
Y185
E
R
L
T
W
H
A
Y
P
E
E
S
E
S
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05205
206
23167
F193
I
P
R
M
V
I
H
F
Y
E
E
R
L
S
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q946J8
445
48626
R309
K
E
L
D
K
N
S
R
F
I
G
A
K
R
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.2
67.1
98.9
N.A.
97.9
N.A.
N.A.
64.4
N.A.
77.8
N.A.
N.A.
46.1
N.A.
N.A.
N.A.
Protein Similarity:
100
73.3
67.1
99.4
N.A.
99.4
N.A.
N.A.
75.9
N.A.
86.9
N.A.
N.A.
62.1
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
N.A.
N.A.
0
N.A.
80
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
N.A.
N.A.
26.6
N.A.
100
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
28.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
23
0
0
56
0
0
0
0
56
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% C
% Asp:
0
0
0
12
0
0
0
0
0
0
45
0
0
0
0
% D
% Glu:
56
12
0
0
0
0
23
23
0
67
23
0
56
0
0
% E
% Phe:
0
0
0
0
23
0
0
12
12
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
56
12
0
0
0
0
0
23
0
0
% H
% Ile:
34
0
23
0
0
12
0
0
0
12
0
0
0
0
0
% I
% Lys:
12
0
0
0
12
0
0
0
0
0
0
0
12
0
56
% K
% Leu:
0
0
67
0
0
0
0
0
0
23
0
0
12
0
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
0
0
0
0
45
0
% N
% Pro:
0
12
0
0
0
0
0
0
56
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
56
12
0
0
0
0
12
23
0
0
12
0
12
12
% R
% Ser:
0
0
0
0
0
0
12
0
0
0
0
12
0
45
0
% S
% Thr:
0
0
0
56
0
0
0
0
0
0
23
0
0
0
0
% T
% Val:
0
23
0
0
12
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
56
0
0
0
0
0
0
23
0
0
12
% W
% Tyr:
0
0
0
0
0
23
0
56
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _