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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP5
All Species:
26.97
Human Site:
T289
Identified Species:
65.93
UniProt:
P45974
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45974
NP_001092006.1
858
95786
T289
D
M
L
K
M
Q
K
T
D
K
T
M
T
E
L
Chimpanzee
Pan troglodytes
XP_508970
858
95311
T289
D
M
L
K
M
Q
K
T
D
K
T
M
T
E
L
Rhesus Macaque
Macaca mulatta
XP_001110639
858
95782
T289
D
M
L
K
M
Q
K
T
D
K
T
M
T
E
L
Dog
Lupus familis
XP_543845
858
95876
T289
D
M
L
K
M
Q
K
T
D
K
T
M
T
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P56399
858
95815
T289
D
M
L
K
M
Q
K
T
D
K
T
M
T
E
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416513
832
93209
T288
D
M
L
K
M
Q
K
T
D
K
T
M
T
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624702
793
90372
K280
I
N
I
A
Q
M
E
K
T
D
K
S
M
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189314
790
88932
T278
N
M
M
N
M
E
K
T
D
K
T
M
T
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Y1
797
88355
M274
S
S
M
Q
K
T
E
M
T
T
A
E
R
E
L
Baker's Yeast
Sacchar. cerevisiae
P38237
781
88611
K282
Y
G
I
N
I
Q
E
K
I
A
D
E
K
T
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
99.6
98.5
N.A.
98.3
N.A.
N.A.
N.A.
88.3
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
54.3
Protein Similarity:
100
97.9
99.7
99.4
N.A.
99.1
N.A.
N.A.
N.A.
93.2
N.A.
N.A.
N.A.
N.A.
67.7
N.A.
71.3
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
0
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.8
29
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
60
0
0
0
0
0
0
0
70
10
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
30
0
0
0
0
20
0
80
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
20
0
10
0
0
0
10
0
0
0
0
10
0
% I
% Lys:
0
0
0
60
10
0
70
20
0
70
10
0
10
0
0
% K
% Leu:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
90
% L
% Met:
0
70
20
0
70
10
0
10
0
0
0
70
10
0
0
% M
% Asn:
10
10
0
20
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
10
70
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
10
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
70
20
10
70
0
70
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _