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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP5
All Species:
25.76
Human Site:
Y354
Identified Species:
62.96
UniProt:
P45974
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45974
NP_001092006.1
858
95786
Y354
I
P
D
F
Q
R
K
Y
V
D
K
L
E
K
I
Chimpanzee
Pan troglodytes
XP_508970
858
95311
Y354
I
P
D
F
Q
R
K
Y
V
D
K
L
E
K
I
Rhesus Macaque
Macaca mulatta
XP_001110639
858
95782
Y354
I
P
D
F
Q
R
K
Y
V
D
K
L
E
K
I
Dog
Lupus familis
XP_543845
858
95876
Y354
I
P
D
F
Q
R
K
Y
V
D
K
L
E
K
I
Cat
Felis silvestris
Mouse
Mus musculus
P56399
858
95815
Y354
I
P
D
F
Q
R
K
Y
V
D
K
L
E
K
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416513
832
93209
Y353
I
P
D
F
Q
R
K
Y
V
D
K
L
E
K
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624702
793
90372
F346
I
P
D
F
I
K
R
F
I
D
G
A
S
Q
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189314
790
88932
Y343
I
P
D
F
V
N
R
Y
A
S
K
K
D
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Y1
797
88355
F337
H
S
F
I
S
R
Y
F
S
H
Q
S
L
K
M
Baker's Yeast
Sacchar. cerevisiae
P38237
781
88611
F353
V
P
N
W
S
L
D
F
L
G
S
K
F
P
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
99.6
98.5
N.A.
98.3
N.A.
N.A.
N.A.
88.3
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
54.3
Protein Similarity:
100
97.9
99.7
99.4
N.A.
99.1
N.A.
N.A.
N.A.
93.2
N.A.
N.A.
N.A.
N.A.
67.7
N.A.
71.3
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
40
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.8
29
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
80
0
0
0
10
0
0
70
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
60
10
0
% E
% Phe:
0
0
10
80
0
0
0
30
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
80
0
0
10
10
0
0
0
10
0
0
0
0
0
80
% I
% Lys:
0
0
0
0
0
10
60
0
0
0
70
20
0
70
0
% K
% Leu:
0
0
0
0
0
10
0
0
10
0
0
60
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
90
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
60
0
0
0
0
0
10
0
0
10
0
% Q
% Arg:
0
0
0
0
0
70
20
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
20
0
0
0
10
10
10
10
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
10
0
0
0
60
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _