KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K4
All Species:
27.27
Human Site:
S135
Identified Species:
42.86
UniProt:
P45985
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45985
NP_003001.1
399
44288
S135
M
A
V
K
R
I
R
S
T
V
D
E
K
E
Q
Chimpanzee
Pan troglodytes
Q9XT09
393
43428
I141
Y
S
D
G
E
I
S
I
C
M
E
H
M
D
G
Rhesus Macaque
Macaca mulatta
XP_001114292
410
45566
S146
M
A
V
K
R
I
R
S
T
V
D
E
K
E
Q
Dog
Lupus familis
XP_546627
413
46697
S149
M
A
V
K
R
I
R
S
T
V
D
E
K
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
P47809
397
44095
S133
M
A
V
K
R
I
R
S
T
V
D
E
K
E
Q
Rat
Rattus norvegicus
Q4KSH7
419
47517
R153
I
A
V
K
Q
M
R
R
S
G
N
K
E
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90891
398
44059
I143
Y
S
D
G
E
I
S
I
C
M
E
H
M
D
G
Frog
Xenopus laevis
Q07192
446
50082
S182
M
A
V
K
R
I
R
S
T
V
D
E
K
E
Q
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
R110
G
V
I
M
A
V
K
R
I
R
A
T
V
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477353
424
47515
S155
M
A
V
K
R
I
R
S
T
V
D
E
K
E
Q
Honey Bee
Apis mellifera
XP_394054
436
49631
S170
M
A
V
K
R
I
R
S
T
V
D
E
R
E
Q
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
R112
R
E
Q
I
R
L
L
R
E
H
D
T
I
V
K
Sea Urchin
Strong. purpuratus
XP_794490
382
43817
Q131
S
T
V
D
E
K
D
Q
K
Q
L
L
M
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJV0
356
39818
I105
M
K
V
I
Q
M
N
I
Q
E
E
I
R
K
Q
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
L393
M
A
T
K
E
V
R
L
E
L
D
E
A
K
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.3
97.3
89.3
N.A.
97.9
41.7
N.A.
N.A.
36.5
77.3
48.3
N.A.
54
55.9
44.6
55.8
Protein Similarity:
100
53.6
97.3
90.5
N.A.
98.2
57.2
N.A.
N.A.
53.8
80.9
64.4
N.A.
65.8
68.8
61.6
71.1
P-Site Identity:
100
6.6
100
100
N.A.
100
33.3
N.A.
N.A.
6.6
100
0
N.A.
100
93.3
13.3
6.6
P-Site Similarity:
100
33.3
100
100
N.A.
100
80
N.A.
N.A.
33.3
100
20
N.A.
100
100
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.3
38.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
0
7
0
0
0
0
0
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% C
% Asp:
0
0
14
7
0
0
7
0
0
0
60
0
0
20
0
% D
% Glu:
0
7
0
0
27
0
0
0
14
7
20
54
7
54
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
7
0
0
14
0
0
0
0
0
7
0
0
0
0
14
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
14
0
0
0
% H
% Ile:
7
0
7
14
0
60
0
20
7
0
0
7
7
0
0
% I
% Lys:
0
7
0
60
0
7
7
0
7
0
0
7
40
14
7
% K
% Leu:
0
0
0
0
0
7
7
7
0
7
7
7
0
0
7
% L
% Met:
60
0
0
7
0
14
0
0
0
14
0
0
20
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
7
0
0
7
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
14
0
0
7
7
7
0
0
0
0
54
% Q
% Arg:
7
0
0
0
54
0
60
20
0
7
0
0
14
0
0
% R
% Ser:
7
14
0
0
0
0
14
47
7
0
0
0
0
0
0
% S
% Thr:
0
7
7
0
0
0
0
0
47
0
0
14
0
0
7
% T
% Val:
0
7
67
0
0
14
0
0
0
47
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _