KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K4
All Species:
19.7
Human Site:
T318
Identified Species:
30.95
UniProt:
P45985
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45985
NP_003001.1
399
44288
T318
N
S
V
F
D
Q
L
T
Q
V
V
K
G
D
P
Chimpanzee
Pan troglodytes
Q9XT09
393
43428
E312
R
P
P
M
A
I
F
E
L
L
D
Y
I
V
N
Rhesus Macaque
Macaca mulatta
XP_001114292
410
45566
T329
N
S
V
F
D
Q
L
T
Q
V
V
K
G
D
P
Dog
Lupus familis
XP_546627
413
46697
T332
N
S
V
F
D
Q
L
T
Q
V
V
K
G
D
P
Cat
Felis silvestris
Mouse
Mus musculus
P47809
397
44095
T316
N
S
V
F
D
Q
L
T
Q
V
V
K
G
D
P
Rat
Rattus norvegicus
Q4KSH7
419
47517
L332
C
K
T
D
F
E
V
L
T
K
V
L
Q
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90891
398
44059
E318
R
P
A
M
A
I
F
E
L
L
D
Y
I
V
N
Frog
Xenopus laevis
Q07192
446
50082
T365
N
S
V
F
D
Q
L
T
Q
V
V
K
G
D
P
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
R281
M
I
E
L
A
I
L
R
F
P
Y
D
S
W
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477353
424
47515
Q338
S
V
F
E
Q
L
C
Q
V
V
Q
G
E
P
P
Honey Bee
Apis mellifera
XP_394054
436
49631
Q353
S
V
F
E
Q
L
Y
Q
V
V
Q
G
D
P
P
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
V283
F
D
Q
I
A
T
V
V
S
G
D
P
P
I
L
Sea Urchin
Strong. purpuratus
XP_794490
382
43817
V302
P
Y
P
K
W
N
S
V
F
E
Q
L
S
Q
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJV0
356
39818
N276
L
E
S
E
D
Q
Q
N
P
P
S
F
Y
E
L
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
S574
E
T
Y
D
N
I
F
S
Q
L
S
A
I
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.3
97.3
89.3
N.A.
97.9
41.7
N.A.
N.A.
36.5
77.3
48.3
N.A.
54
55.9
44.6
55.8
Protein Similarity:
100
53.6
97.3
90.5
N.A.
98.2
57.2
N.A.
N.A.
53.8
80.9
64.4
N.A.
65.8
68.8
61.6
71.1
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
N.A.
0
100
6.6
N.A.
13.3
13.3
0
0
P-Site Similarity:
100
6.6
100
100
N.A.
100
26.6
N.A.
N.A.
6.6
100
6.6
N.A.
20
20
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.3
38.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
27
0
0
0
0
0
0
7
0
0
0
% A
% Cys:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
14
40
0
0
0
0
0
20
7
7
34
7
% D
% Glu:
7
7
7
20
0
7
0
14
0
7
0
0
7
14
7
% E
% Phe:
7
0
14
34
7
0
20
0
14
0
0
7
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
0
14
34
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
0
27
0
0
0
0
0
0
20
7
0
% I
% Lys:
0
7
0
7
0
0
0
0
0
7
0
34
0
0
0
% K
% Leu:
7
0
0
7
0
14
40
7
14
20
0
14
0
0
14
% L
% Met:
7
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
34
0
0
0
7
7
0
7
0
0
0
0
0
0
14
% N
% Pro:
7
14
14
0
0
0
0
0
7
14
0
7
7
14
47
% P
% Gln:
0
0
7
0
14
40
7
14
40
0
20
0
7
7
0
% Q
% Arg:
14
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
14
34
7
0
0
0
7
7
7
0
14
0
14
0
0
% S
% Thr:
0
7
7
0
0
7
0
34
7
0
0
0
0
0
0
% T
% Val:
0
14
34
0
0
0
14
14
14
47
40
0
0
20
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
7
7
0
0
0
7
0
0
0
7
14
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _