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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHKA2
All Species:
33.33
Human Site:
Y499
Identified Species:
66.67
UniProt:
P46019
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46019
NP_000283.1
1235
138408
Y499
M
N
L
S
G
R
P
Y
R
H
I
G
V
L
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001084454
1235
138543
Y499
M
N
L
S
G
R
P
Y
R
H
I
G
V
L
G
Dog
Lupus familis
XP_537974
1231
137964
Y499
M
K
L
S
G
R
P
Y
R
H
I
G
V
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWJ3
1235
138474
Y499
M
K
L
S
G
R
P
Y
R
H
I
G
V
L
G
Rat
Rattus norvegicus
Q64649
1242
139137
Y500
M
K
L
S
G
R
P
Y
R
L
M
G
V
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514153
1339
149225
Y602
L
K
L
S
G
R
P
Y
R
H
I
G
V
L
G
Chicken
Gallus gallus
XP_416811
1230
138135
H499
M
K
L
S
G
R
P
H
R
H
I
G
V
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684044
1205
135186
Y499
L
N
L
S
G
R
P
Y
R
H
I
G
V
L
G
Tiger Blowfish
Takifugu rubipres
Q9W6R1
1229
137905
Y499
L
S
L
S
G
R
P
Y
R
H
I
G
V
L
G
Fruit Fly
Dros. melanogaster
Q9W391
1247
140494
S499
L
G
L
S
G
R
K
S
R
D
V
G
I
L
S
Honey Bee
Apis mellifera
XP_623102
1197
134419
R488
H
L
Y
T
Y
L
G
R
N
K
K
L
G
L
S
Nematode Worm
Caenorhab. elegans
P34335
1226
139432
D503
N
L
S
G
R
P
L
D
R
P
I
G
L
L
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
95.2
N.A.
90.8
67.6
N.A.
79.6
81.1
N.A.
73.4
71.9
51.2
49.7
40.4
N.A.
Protein Similarity:
100
N.A.
99.5
97.5
N.A.
94.8
80.7
N.A.
85.6
89.4
N.A.
83.8
82.2
68.3
67.4
58.9
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
80
N.A.
86.6
86.6
N.A.
93.3
86.6
46.6
6.6
26.6
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
86.6
N.A.
93.3
93.3
N.A.
100
100
66.6
13.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
9
84
0
9
0
0
0
0
92
9
0
75
% G
% His:
9
0
0
0
0
0
0
9
0
67
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
75
0
9
0
0
% I
% Lys:
0
42
0
0
0
0
9
0
0
9
9
0
0
0
0
% K
% Leu:
34
17
84
0
0
9
9
0
0
9
0
9
9
100
0
% L
% Met:
50
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
25
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
75
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
84
0
9
92
0
0
0
0
0
0
% R
% Ser:
0
9
9
84
0
0
0
9
0
0
0
0
0
0
25
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
0
75
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
9
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _