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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A1
All Species:
26.06
Human Site:
S275
Identified Species:
47.78
UniProt:
P46059
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46059
NP_005064.1
708
78806
S275
K
Y
D
E
R
L
I
S
Q
I
K
M
V
T
R
Chimpanzee
Pan troglodytes
XP_522705
841
92470
S408
K
Y
D
E
R
L
I
S
Q
I
K
M
V
T
R
Rhesus Macaque
Macaca mulatta
NP_001028071
708
78697
S275
K
Y
D
E
R
L
I
S
Q
I
K
M
V
M
R
Dog
Lupus familis
XP_545128
740
82954
M305
K
Y
P
K
Q
L
I
M
D
V
K
A
L
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIP7
709
78530
S275
K
Y
D
E
R
L
I
S
Q
I
K
M
V
T
K
Rat
Rattus norvegicus
P51574
710
78910
S275
K
Y
D
E
R
L
I
S
Q
I
K
I
M
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506250
701
78013
T273
K
Y
D
E
R
L
I
T
Q
T
K
M
V
L
K
Chicken
Gallus gallus
NP_989696
714
79285
A281
K
Y
D
K
R
L
I
A
Q
T
K
M
V
L
K
Frog
Xenopus laevis
NP_001080398
682
75781
T248
K
Y
Q
K
R
L
I
T
E
V
K
M
V
T
K
Zebra Danio
Brachydanio rerio
NP_932330
718
80447
A282
K
Y
D
K
L
L
I
A
Q
V
K
M
V
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91679
743
82227
Q282
T
V
G
S
R
M
V
Q
E
T
K
C
L
G
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01840
701
77949
D265
E
H
S
Q
K
M
I
D
S
T
R
G
L
L
N
Sea Urchin
Strong. purpuratus
XP_792746
715
78418
E284
K
Y
G
A
A
L
I
E
D
I
K
V
L
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.1
92.3
47.1
N.A.
82.9
83.5
N.A.
71.4
63.4
49.7
59
N.A.
35.9
N.A.
34
41.4
Protein Similarity:
100
83.3
95.3
64.3
N.A.
88.8
90.6
N.A.
83
76.7
66.9
74.3
N.A.
55.9
N.A.
54.2
58.8
P-Site Identity:
100
100
93.3
46.6
N.A.
93.3
80
N.A.
73.3
66.6
60
60
N.A.
20
N.A.
6.6
40
P-Site Similarity:
100
100
93.3
73.3
N.A.
100
100
N.A.
86.6
86.6
93.3
86.6
N.A.
46.6
N.A.
53.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
16
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
62
0
0
0
0
8
16
0
0
0
0
0
0
% D
% Glu:
8
0
0
47
0
0
0
8
16
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
16
0
0
0
0
0
0
0
0
8
0
8
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
93
0
0
47
0
8
0
0
0
% I
% Lys:
85
0
0
31
8
0
0
0
0
0
93
0
0
0
47
% K
% Leu:
0
0
0
0
8
85
0
0
0
0
0
0
31
31
0
% L
% Met:
0
0
0
0
0
16
0
8
0
0
0
62
8
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
8
8
0
0
8
62
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
70
0
0
0
0
0
8
0
0
0
39
% R
% Ser:
0
0
8
8
0
0
0
39
8
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
16
0
31
0
0
0
47
0
% T
% Val:
0
8
0
0
0
0
8
0
0
24
0
8
62
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
85
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _