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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A1
All Species:
15.15
Human Site:
T533
Identified Species:
27.78
UniProt:
P46059
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46059
NP_005064.1
708
78806
T533
K
G
F
T
I
S
S
T
E
I
P
P
Q
C
Q
Chimpanzee
Pan troglodytes
XP_522705
841
92470
T666
K
G
F
T
I
S
S
T
E
I
P
P
Q
C
Q
Rhesus Macaque
Macaca mulatta
NP_001028071
708
78697
T533
K
G
F
T
I
S
S
T
E
I
P
P
Q
C
Q
Dog
Lupus familis
XP_545128
740
82954
H571
S
G
E
Y
P
V
V
H
C
R
T
E
D
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIP7
709
78530
T534
K
Q
Y
T
I
N
T
T
A
V
A
P
T
C
L
Rat
Rattus norvegicus
P51574
710
78910
E535
D
Y
T
I
N
T
T
E
I
A
P
N
C
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506250
701
78013
T524
F
F
P
S
G
V
K
T
I
M
I
N
D
K
Q
Chicken
Gallus gallus
NP_989696
714
79285
V539
G
G
R
T
Y
D
I
V
I
T
A
G
S
T
N
Frog
Xenopus laevis
NP_001080398
682
75781
S510
K
R
G
K
I
T
A
S
C
L
T
E
L
N
T
Zebra Danio
Brachydanio rerio
NP_932330
718
80447
G533
V
N
F
T
I
F
D
G
G
D
G
K
C
H
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91679
743
82227
F545
L
H
R
I
T
P
G
F
A
R
V
D
I
N
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01840
701
77949
G527
P
N
V
R
L
Y
W
G
P
K
N
S
C
S
G
Sea Urchin
Strong. purpuratus
XP_792746
715
78418
G528
S
V
Y
G
V
P
V
G
N
A
S
K
V
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.1
92.3
47.1
N.A.
82.9
83.5
N.A.
71.4
63.4
49.7
59
N.A.
35.9
N.A.
34
41.4
Protein Similarity:
100
83.3
95.3
64.3
N.A.
88.8
90.6
N.A.
83
76.7
66.9
74.3
N.A.
55.9
N.A.
54.2
58.8
P-Site Identity:
100
100
100
6.6
N.A.
40
6.6
N.A.
13.3
13.3
13.3
20
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
100
6.6
N.A.
66.6
20
N.A.
26.6
13.3
40
20
N.A.
0
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
16
16
16
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
16
0
0
0
24
31
0
% C
% Asp:
8
0
0
0
0
8
8
0
0
8
0
8
16
0
8
% D
% Glu:
0
0
8
0
0
0
0
8
24
0
0
16
0
0
0
% E
% Phe:
8
8
31
0
0
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
39
8
8
8
0
8
24
8
0
8
8
0
0
16
% G
% His:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
16
47
0
8
0
24
24
8
0
8
0
0
% I
% Lys:
39
0
0
8
0
0
8
0
0
8
0
16
0
16
0
% K
% Leu:
8
0
0
0
8
0
0
0
0
8
0
0
8
8
16
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
16
0
0
8
8
0
0
8
0
8
16
0
16
8
% N
% Pro:
8
0
8
0
8
16
0
0
8
0
31
31
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
24
0
31
% Q
% Arg:
0
8
16
8
0
0
0
0
0
16
0
0
0
0
0
% R
% Ser:
16
0
0
8
0
24
24
8
0
0
8
8
8
16
8
% S
% Thr:
0
0
8
47
8
16
16
39
0
8
16
0
8
8
8
% T
% Val:
8
8
8
0
8
16
16
8
0
8
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
16
8
8
8
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _