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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A1
All Species:
9.7
Human Site:
Y470
Identified Species:
17.78
UniProt:
P46059
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46059
NP_005064.1
708
78806
Y470
L
V
W
A
P
N
H
Y
Q
V
V
K
D
G
L
Chimpanzee
Pan troglodytes
XP_522705
841
92470
Y603
L
V
W
A
P
N
H
Y
Q
V
V
K
D
G
L
Rhesus Macaque
Macaca mulatta
NP_001028071
708
78697
Y470
L
V
W
A
P
N
H
Y
R
V
V
K
D
D
L
Dog
Lupus familis
XP_545128
740
82954
L500
E
E
K
N
W
Y
S
L
I
I
R
E
D
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIP7
709
78530
Q470
L
L
V
W
E
P
S
Q
Y
R
V
V
K
D
G
Rat
Rattus norvegicus
P51574
710
78910
L470
L
L
V
W
G
P
N
L
Y
R
V
V
K
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506250
701
78013
T468
L
W
S
P
S
E
F
T
L
L
E
N
D
L
N
Chicken
Gallus gallus
NP_989696
714
79285
G476
T
I
K
N
A
A
A
G
I
V
S
S
L
R
S
Frog
Xenopus laevis
NP_001080398
682
75781
L443
E
K
S
S
F
S
L
L
V
Y
S
E
E
N
S
Zebra Danio
Brachydanio rerio
NP_932330
718
80447
L475
A
A
G
M
R
N
T
L
D
D
L
T
E
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91679
743
82227
L482
Y
F
L
A
Q
D
K
L
V
E
F
A
D
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01840
701
77949
K465
E
V
V
K
F
D
Y
K
V
E
K
T
D
N
G
Sea Urchin
Strong. purpuratus
XP_792746
715
78418
I473
S
Q
L
V
E
S
V
I
V
Y
S
S
A
N
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.1
92.3
47.1
N.A.
82.9
83.5
N.A.
71.4
63.4
49.7
59
N.A.
35.9
N.A.
34
41.4
Protein Similarity:
100
83.3
95.3
64.3
N.A.
88.8
90.6
N.A.
83
76.7
66.9
74.3
N.A.
55.9
N.A.
54.2
58.8
P-Site Identity:
100
100
86.6
13.3
N.A.
13.3
13.3
N.A.
13.3
6.6
0
6.6
N.A.
26.6
N.A.
13.3
0
P-Site Similarity:
100
100
93.3
26.6
N.A.
20
26.6
N.A.
20
13.3
26.6
20
N.A.
33.3
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
31
8
8
8
0
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
16
0
0
8
8
0
0
54
24
0
% D
% Glu:
24
8
0
0
16
8
0
0
0
16
8
16
16
0
0
% E
% Phe:
0
8
0
0
16
0
8
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
8
0
8
0
0
8
0
0
0
0
0
31
24
% G
% His:
0
0
0
0
0
0
24
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
16
8
0
0
0
0
0
% I
% Lys:
0
8
16
8
0
0
8
8
0
0
8
24
16
8
8
% K
% Leu:
47
16
16
0
0
0
8
39
8
8
8
0
8
8
31
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
0
31
8
0
0
0
0
8
0
24
8
% N
% Pro:
0
0
0
8
24
16
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
8
0
0
8
0
0
8
16
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
8
0
0
0
8
16
8
0
0
8
0
% R
% Ser:
8
0
16
8
8
16
16
0
0
0
24
16
0
0
16
% S
% Thr:
8
0
0
0
0
0
8
8
0
0
0
16
0
0
0
% T
% Val:
0
31
24
8
0
0
8
0
31
31
39
16
0
0
0
% V
% Trp:
0
8
24
16
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
8
24
16
16
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _