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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A1
All Species:
13.94
Human Site:
Y518
Identified Species:
25.56
UniProt:
P46059
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46059
NP_005064.1
708
78806
Y518
S
S
Y
N
A
S
T
Y
Q
F
F
P
S
G
I
Chimpanzee
Pan troglodytes
XP_522705
841
92470
Y651
S
S
Y
S
A
S
T
Y
Q
F
F
P
S
G
I
Rhesus Macaque
Macaca mulatta
NP_001028071
708
78697
Y518
S
S
N
N
A
S
N
Y
Q
F
F
P
S
G
V
Dog
Lupus familis
XP_545128
740
82954
V556
S
V
G
E
D
Y
G
V
S
A
Y
T
T
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIP7
709
78530
Y519
T
S
H
N
A
S
G
Y
K
F
L
P
S
G
E
Rat
Rattus norvegicus
P51574
710
78910
Q520
S
H
S
A
S
N
Y
Q
F
F
P
S
G
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506250
701
78013
P509
S
N
F
Q
D
V
L
P
R
N
A
S
E
Y
E
Chicken
Gallus gallus
NP_989696
714
79285
I524
G
I
L
E
E
T
S
I
S
N
Y
S
P
F
S
Frog
Xenopus laevis
NP_001080398
682
75781
D495
T
V
S
A
R
R
G
D
V
S
N
Y
V
T
L
Zebra Danio
Brachydanio rerio
NP_932330
718
80447
Y518
D
P
L
D
A
S
V
Y
L
L
V
P
H
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91679
743
82227
L530
S
Q
E
P
P
L
T
L
D
K
G
N
V
P
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01840
701
77949
V512
K
S
G
S
Y
V
D
V
I
P
G
I
I
S
D
Sea Urchin
Strong. purpuratus
XP_792746
715
78418
L513
L
N
N
V
S
S
S
L
D
V
E
P
G
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.1
92.3
47.1
N.A.
82.9
83.5
N.A.
71.4
63.4
49.7
59
N.A.
35.9
N.A.
34
41.4
Protein Similarity:
100
83.3
95.3
64.3
N.A.
88.8
90.6
N.A.
83
76.7
66.9
74.3
N.A.
55.9
N.A.
54.2
58.8
P-Site Identity:
100
93.3
80
6.6
N.A.
60
13.3
N.A.
6.6
0
0
33.3
N.A.
13.3
N.A.
6.6
13.3
P-Site Similarity:
100
100
86.6
20
N.A.
80
26.6
N.A.
26.6
20
13.3
40
N.A.
13.3
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
39
0
0
0
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
16
0
8
8
16
0
0
0
0
0
8
% D
% Glu:
0
0
8
16
8
0
0
0
0
0
8
0
8
0
16
% E
% Phe:
0
0
8
0
0
0
0
0
8
39
24
0
0
8
0
% F
% Gly:
8
0
16
0
0
0
24
0
0
0
16
0
16
39
0
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
8
0
0
8
8
0
16
% I
% Lys:
8
0
0
0
0
0
0
0
8
8
0
0
0
0
16
% K
% Leu:
8
0
16
0
0
8
8
16
8
8
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
16
16
24
0
8
8
0
0
16
8
8
0
0
0
% N
% Pro:
0
8
0
8
8
0
0
8
0
8
8
47
8
8
0
% P
% Gln:
0
8
0
8
0
0
0
8
24
0
0
0
0
16
16
% Q
% Arg:
0
0
0
0
8
8
0
0
8
0
0
0
0
0
0
% R
% Ser:
54
39
16
16
16
47
16
0
16
8
0
24
31
8
8
% S
% Thr:
16
0
0
0
0
8
24
0
0
0
0
8
8
8
0
% T
% Val:
0
16
0
8
0
16
8
16
8
8
8
0
16
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
0
8
8
8
39
0
0
16
8
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _