Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RANGAP1 All Species: 30.61
Human Site: S29 Identified Species: 51.79
UniProt: P46060 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46060 NP_002874.1 587 63542 S29 Q L S F K G K S L K L N T A E
Chimpanzee Pan troglodytes XP_001169198 587 63551 S29 Q L S F K G K S L K L N T A E
Rhesus Macaque Macaca mulatta XP_001099367 1074 115836 S84 Q L S F K G K S L K L N T A E
Dog Lupus familis XP_538355 1323 142434 S29 Q L S F K G K S L K L N T A E
Cat Felis silvestris
Mouse Mus musculus P46061 589 63598 G29 Q L S F K G K G L K L N T A E
Rat Rattus norvegicus NP_001012199 431 46388
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509116 589 63641 S29 Q L S F K G K S L K L N T A E
Chicken Gallus gallus NP_001006237 580 63057 S29 Q L S F K G Q S L K L N T A E
Frog Xenopus laevis O13066 580 62889 T29 E L S F K G K T L K L N T A Q
Zebra Danio Brachydanio rerio NP_001070084 570 61996 G29 E L S Y K G K G L K L D N A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VIW3 596 66051 N29 E N K V L S W N T A A D V Q D
Honey Bee Apis mellifera XP_395378 580 63771 S31 G V S F A K K S L K L D T E E
Nematode Worm Caenorhab. elegans P34342 960 105635 Q50 T L S F F G K Q L K L D T E E
Sea Urchin Strong. purpuratus XP_001185909 387 41323
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 52.7 41.4 N.A. 88.6 66.6 N.A. 83.6 81.7 67.9 60.8 N.A. 32.3 43.6 25 40.7
Protein Similarity: 100 99.1 53.7 43 N.A. 95.5 70.6 N.A. 91.5 91.6 83.8 78 N.A. 53.1 59.9 38.2 54.8
P-Site Identity: 100 100 100 100 N.A. 93.3 0 N.A. 100 93.3 80 60 N.A. 0 60 66.6 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 0 N.A. 100 100 100 86.6 N.A. 26.6 73.3 73.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 8 8 0 0 65 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 29 0 0 8 % D
% Glu: 22 0 0 0 0 0 0 0 0 0 0 0 0 15 65 % E
% Phe: 0 0 0 72 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 72 0 15 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 65 8 72 0 0 79 0 0 0 0 0 % K
% Leu: 0 72 0 0 8 0 0 0 79 0 79 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 8 0 0 0 58 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 50 0 0 0 0 0 8 8 0 0 0 0 0 8 15 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 79 0 0 8 0 50 0 0 0 0 0 0 0 % S
% Thr: 8 0 0 0 0 0 0 8 8 0 0 0 72 0 0 % T
% Val: 0 8 0 8 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _