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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RANGAP1 All Species: 37.88
Human Site: S356 Identified Species: 64.1
UniProt: P46060 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46060 NP_002874.1 587 63542 S356 N M A K V L A S L S D D E D E
Chimpanzee Pan troglodytes XP_001169198 587 63551 S356 N M A K V L A S L S D D E D E
Rhesus Macaque Macaca mulatta XP_001099367 1074 115836 S411 N M A K V L A S L S D D E D E
Dog Lupus familis XP_538355 1323 142434 S356 N M A R V L A S L S D D E G E
Cat Felis silvestris
Mouse Mus musculus P46061 589 63598 S356 N M A K V L A S L S D D E G E
Rat Rattus norvegicus NP_001012199 431 46388 R239 F A I N P L L R V I N L N D N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509116 589 63641 S356 N M A H V L A S L S D D E G D
Chicken Gallus gallus NP_001006237 580 63057 S356 N M A T V L G S L S D D E G E
Frog Xenopus laevis O13066 580 62889 S356 N M A N I L G S L S D D E D E
Zebra Danio Brachydanio rerio NP_001070084 570 61996 S356 N M A D K L G S L S D D E G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VIW3 596 66051 Q370 D E Y Q A D K Q D A D Y E E E
Honey Bee Apis mellifera XP_395378 580 63771 S359 T I S E R I G S L S T L D D D
Nematode Worm Caenorhab. elegans P34342 960 105635 S384 G D D E L L S S D E E E E Q G
Sea Urchin Strong. purpuratus XP_001185909 387 41323 A195 N R L E N P G A T A L A K A F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 52.7 41.4 N.A. 88.6 66.6 N.A. 83.6 81.7 67.9 60.8 N.A. 32.3 43.6 25 40.7
Protein Similarity: 100 99.1 53.7 43 N.A. 95.5 70.6 N.A. 91.5 91.6 83.8 78 N.A. 53.1 59.9 38.2 54.8
P-Site Identity: 100 100 100 86.6 N.A. 93.3 13.3 N.A. 80 80 80 73.3 N.A. 20 26.6 20 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 26.6 N.A. 86.6 80 86.6 73.3 N.A. 46.6 66.6 53.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 65 0 8 0 43 8 0 15 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 8 8 0 8 0 0 15 0 72 65 8 43 15 % D
% Glu: 0 8 0 22 0 0 0 0 0 8 8 8 79 8 65 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 8 0 0 0 0 0 36 0 0 0 0 0 0 36 8 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 8 8 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 29 8 0 8 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 8 0 8 79 8 0 72 0 8 15 0 0 0 % L
% Met: 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 72 0 0 15 8 0 0 0 0 0 8 0 8 0 8 % N
% Pro: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 8 0 0 0 0 0 8 0 % Q
% Arg: 0 8 0 8 8 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 0 8 0 0 0 8 79 0 72 0 0 0 0 0 % S
% Thr: 8 0 0 8 0 0 0 0 8 0 8 0 0 0 0 % T
% Val: 0 0 0 0 50 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _