KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RANGAP1
All Species:
20.3
Human Site:
S427
Identified Species:
34.36
UniProt:
P46060
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46060
NP_002874.1
587
63542
S427
G
E
P
A
P
V
L
S
S
P
P
P
A
D
V
Chimpanzee
Pan troglodytes
XP_001169198
587
63551
S427
G
E
P
A
P
V
L
S
S
P
P
P
A
D
I
Rhesus Macaque
Macaca mulatta
XP_001099367
1074
115836
S481
G
E
P
A
P
V
L
S
S
P
P
P
A
D
V
Dog
Lupus familis
XP_538355
1323
142434
S427
E
E
P
A
P
V
L
S
S
P
P
P
A
D
V
Cat
Felis silvestris
Mouse
Mus musculus
P46061
589
63598
S429
G
E
P
A
P
V
L
S
S
P
T
P
T
D
L
Rat
Rattus norvegicus
NP_001012199
431
46388
V276
I
N
F
G
D
C
L
V
R
S
K
G
A
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509116
589
63641
C429
G
E
P
A
P
V
I
C
S
P
P
P
V
D
V
Chicken
Gallus gallus
NP_001006237
580
63057
V420
G
S
Q
D
S
T
P
V
P
S
P
P
V
D
V
Frog
Xenopus laevis
O13066
580
62889
P420
S
G
S
A
P
A
S
P
P
K
L
P
V
D
A
Zebra Danio
Brachydanio rerio
NP_001070084
570
61996
S405
N
Q
F
S
T
P
P
S
A
P
R
T
P
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIW3
596
66051
F430
N
A
Y
T
T
K
L
F
N
D
T
T
N
S
M
Honey Bee
Apis mellifera
XP_395378
580
63771
D404
N
E
S
K
E
N
R
D
I
N
K
D
T
I
I
Nematode Worm
Caenorhab. elegans
P34342
960
105635
K586
N
G
L
G
I
G
G
K
Q
I
A
K
S
L
T
Sea Urchin
Strong. purpuratus
XP_001185909
387
41323
Y232
A
L
A
E
A
V
E
Y
S
H
N
L
K
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
52.7
41.4
N.A.
88.6
66.6
N.A.
83.6
81.7
67.9
60.8
N.A.
32.3
43.6
25
40.7
Protein Similarity:
100
99.1
53.7
43
N.A.
95.5
70.6
N.A.
91.5
91.6
83.8
78
N.A.
53.1
59.9
38.2
54.8
P-Site Identity:
100
93.3
100
93.3
N.A.
80
13.3
N.A.
80
33.3
26.6
26.6
N.A.
6.6
6.6
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
13.3
N.A.
86.6
33.3
26.6
46.6
N.A.
20
13.3
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
50
8
8
0
0
8
0
8
0
36
0
15
% A
% Cys:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
8
0
8
0
8
0
65
0
% D
% Glu:
8
50
0
8
8
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
15
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
43
15
0
15
0
8
8
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
8
0
8
8
0
0
0
15
15
% I
% Lys:
0
0
0
8
0
8
0
8
0
8
15
8
8
0
0
% K
% Leu:
0
8
8
0
0
0
50
0
0
0
8
8
0
8
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
29
8
0
0
0
8
0
0
8
8
8
0
8
0
0
% N
% Pro:
0
0
43
0
50
8
15
8
15
50
43
58
8
0
0
% P
% Gln:
0
8
8
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% R
% Ser:
8
8
15
8
8
0
8
43
50
15
0
0
8
8
0
% S
% Thr:
0
0
0
8
15
8
0
0
0
0
15
15
15
0
8
% T
% Val:
0
0
0
0
0
50
0
15
0
0
0
0
22
8
43
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _